clinical research companies usa

Top 17 Clinical Research Organizations (CRO) in 2023

In clinical research and treatment development, clinical research organizations (CROs) are frequently a sponsor’s most important partner and ally.

Depending on the nature of the clinical trial, and your existing capabilities as a sponsor to run the trial, the CRO company of your choice will typically be responsible for facilitating most of the micro and macro processes that go into designing and running a successful clinical trial.

When contracting a CRO to help you with your trial, you are transferring over a large portion of responsibility into the hands of your clinical research partner. The CRO of your choice will have the responsibility to control a variety of factors and processes of a clinical trial, and depending on their expertise, team structures, service offerings, internal resources and many other capabilities.

Your ability to find and contract a top CRO company that is the right fit for your unique trial will be a determinant of whether or not you will be able to operate a high-quality clinical trial that meets your expected timelines, budget and delivers a top-notch patient experience.

At ClaraHealth (a patient-centric recruitment acceleration platform) , we have put together an extensive list of the top CRO companies in the US and around the world.

This is not a cro rankings list, but rather a compiled list of some of the top clinical research organizations around the world. We have highlighted their strengths and core service offerings to make it easier for you to find the right fit clinical research partner.

In addition, we’ve put together a list of 9 fundamental questions to ask the prospective clinical research organization , which will help you to save time and ensure a right fit in picking the CRO.

Formerly known as Quintiles and IMS Health, IQVIA is one of the largest CROs in the world, with a large range of service offerings to help advance clinical research.

The company was founded in North Carolina in 1982, and has since grown to over 88,000 employees in more than 100 countries.

Some clinical trial solutions offered by IQVIA include:

• Assistance with protocol design
• Design of phase 1 clinical trials
• Assessment and improvement of phase 2 and 3 clinical trials
• Site identification & selection
• Patient recruitment
• Access to global laboratories via their wholly owned subsidiary Q2 Solutions

Parexel is a global clinical research organization that was founded in 1982, and specializes in conducting clinical studies on behalf of its pharmaceutical partners in order to accelerate and ensure the drug approval process of up-and-coming potential treatments. It currently operates in more than 50 countries, and is run by more than 18,000 employees around the world.

The company has a wide range of service offerings, covering nearly every type of clinical trial service to assist sponsors in running successful clinical studies.

Some clinical trial solutions offered by Parexel include:

• Clinical trial design and development for early phase, phase 2 & 3, and late phase clinical trials
• Clinical data management
• Decentralized clinical trials
• Clinical supply chain management
• Medical writing
• Regulatory affairs consulting
• Pharmacovigilance

3. PRA Health Sciences

PRA Health Sciences is one of the largest contract research organizations in the world. Founded in 1976 under the name “Anti-Inflammatory Drug Study Group”, the company was renamed to PRA in 1982. PRA Health Sciences employees more than 17,000 people, and provides coverage to more than 90 countries.

In 2021, PRA Health Sciences was acquired by the Ireland-headquartered global CRO leader ICON, which is also reviewed in this list.

Some clinical trial solutions offered by PRA Health Sciences include:

• Decentralized Clinical Trials Platform
• Protocol Consultation & Study Design
• Onsite Support services
• Customized Solutions for Biotech (such as asset valuation, regulatory strategy, engagement and support, drug development strategy and funding solutions)
• Clinical Diagnostics
• Site Commercial Solutions
• PRA’s Laboratories for Drug Development

Headquartered in Ireland, ICON was founded in 1990 in Dublin by co-founders John Climax and Ronan Lambre. The company has since grown to be one of the largest CROs in the world. As of September 2020, the company employs more than 15,000 people in 94 locations and across 40 countries.

ICON offers clinical research services which include consulting, clinical development and commercialization across a wide range of therapeutic areas.

In 2021, ICON acquired PRA Health Sciences, which is another CRO and global leader in clinical research services.

Some clinical trial solutions offered by ICON:

• Commercial Positioning
• Early Phase
• Functional Services Provision
• Laboratories
• Language Services
• Medical Imaging
• Real World Intelligence
• Site & Patient Solutions
• COVID-19 Clinical Operations

5. Syneos Health

Formerly known as InVentiv Health Incorporated and INC Research, Syneos Health is a publicly listed and global contract research organization. The company is based in Morrisville, North Carolina, and specializes in assisting companies with late-stage clinical trials. Syneos Health currently employs more than 25,000 people, and has offices across 91 locations.

In early 2018, INC Research was acquired inVentiv Health, and the merged company was named Syneos Health.

Some clinical trial solutions offered by Syneos Health include:

• Decentralized Clinical Trials Solutions
• Bioanalytical Solutions
• Phase II-III/Phase IIIb-IIIV
• Medical Device Diagnostics
• Clinical Data Management
• Clinical Project Management
• Clinical Monitoring
• Drug Safety & Pharmacovigilance
• Site and Patient Access

6. Labcorp Drug Development (Formerly Covance)

Formerly known as Covance and renamed to Labcorp Drug Development in early 2021, this CRO is one of the largest contract research organizations in the world. The company claims to provide the world’s largest central laboratory network, and has been rated as one of the best places to work for LGBTQ+ equality by the Human Rights Campaign organization in 2018 to 2021. Currently, Labcorp employs over 70,000 people and is able to support clinical research efforts in almost 100 countries around the world.

Some clinical trial solutions offered by Labcorp Drug Development include:

• Preclinical Services
• Clinical Trials
• Clinical Trial Laboratory Services
• Post-Marketing Solutions
• Medical Devices
• Data & Technology

Also known as Pharmaceutical Product Development, PPD is a large global contract research organization headquartered in Wilmington, North Carolina. Started as a one-person consulting firm in 1985, PPD has grown to over 27,000 employees worldwide, and provides a wide range of clinical research services to pharmaceutical and biotech companies.

Some clinical trial solutions offered by PPD include:

• Clinical Development
• Early Development
• Peri- and Post-Approval
• PPD Biotech
• PPD Laboratories
• Product Development and Consulting
• Site and Patient Centric Solutions

8. Fisher Clinical Services

Part of Thermo Fisher Scientific, Fisher Clinical Services is a global clinical research organization with headquarters in Center Valley, Philadelphia.

The company has been in the business of clinical supply chain management for over 20 years, and is focused exclusively on working with the packaging and distribution requirements of clinical trials across the globe.

Some clinical trial solutions offered by Fisher Clinical Services include:

• Biologistics Management
• Cell & Gene Therapy
• Clinical Ancillary Management
• Clinical Label Services
• Clinical Trial Packaging & Storage
• Clinical Supply Optimization Services
• Cold Chain Management & Expertise
• Direct-to-Patient
• Distribution & Logistics
• Strategic Comparator Sourcing
• Public Health Research

Established in 1997 under the name Kiecana Clinical Research, KCR is a full-service contract research organization that provides a variety of services for clinical monitoring, safety & pharmacovigilance, clinical project management, quality assurance and regulatory affairs.

KCR operates globally, and has offices in North America, Western Europe, Central Europe and Eartern Europe. The company currently employs more than 700 staff.

Some clinical trial solutions offered by KCR include:

• Trial Execution

10. Medpace

Founded in 1992 and based in Cincinnati, Ohio, Medpace is a midsize clinical contract research organization. The company has operations in over 45 countries, and employs over 2,800 people. Medpace provides support services for Phase I-IV clinical trials for pharmaceutical and biotechnology companies, which include central laboratory services and regulatory services.

Some clinical trial solutions offered by Medpace include:

• Biostatistics and Data Sciences
• Clinical Trial Management
• Drug Safety and Pharmacovigilance
• Medical Writing
• Quality Assurance
• Regulatory Affairs
• Risk-Based Monitoring
• Medpace Laboratories

11. Clintec

Now in business for over 22 years, Clintec is a medium-sized global contract research organization for pharmaceutical, biotech and medical device industries, with large expertise in oncology and rare diseases.

The company provides the flexibility and agility of a smaller-sized CRO, while also having a wide global coverage that large CRO companies are known for. Clintec is based in more than 50 countries, and was acquired by the leading global CRO IQVIA in late 2018.

Some clinical trial solutions offered by Clintec include:

• Project Management
• Data Management
• Biostatistics
• Global Feasibilities
• Patient Recruitment & Retention

12. Worldwide Clinical Trials

Bringing over 30 years of experience to the clinical research market, Worldwide Clinical Trials is a leading medium-sized global contract research organization. Founded by physicians with a dedication and commitment to advancing medical research, Worldwide Clinical Trials was the first customer-centric CRO.

Currently the company has coverage in more than 60 countries, and has extensive experience in a wide range of therapeutic areas, including central nervous system, metabolic, cardiovascular, oncology, rare diseases and general medicine.

Some clinical trial solutions offered by Worldwide Clinical Trials include:

• Bioanalytical Lab
• Early Phase Development
• Clinical Phase IIB-II Clinical Trials
• Phase IIIB-IV Clinical Trials
• Trial Management Technologies

Named #1 CRO in the world for operational excellence at the 2021 CRO Leadership Awards, CTI Clinical Trial And Consulting Services is a medium-sized global contract research organization that has been serving pharmaceutical companies since 1999.

Based in Covington, Kentucky, CTI has offices around the world in more than 60 countries, with coverage in North America, Europe, Latin America, Middle-East, Africa, and Asia-Pacific regions.

Some clinical trial solutions offered by CTI include:

• Feasibility
• Regulatory Affairs Study Start-Up
• Medical Monitoring
• Safety & Pharmacovigilance
• Clinical Services

14. Wuxi AppTec

Founded in 2000 as WuXi PharmaTech in the city of Wuxi, China, Wuxi AppTec has grown from a single laboratory into a leading global contract research organization with more than 28,000 employees, including 23,000 scientists and more than 30 research & development and manufacturing sites around the world.

With offices in Asia, U.S, Europe and the Middle East, the company is able to provide coverage to more than 30 countries around the world.

Some clinical trial solutions offered by Wuxi AppTec include:

• Small Molecule Drug R&D and Manufacturing
• Cell Therapy and Gene Therapy
• Drug R&D and Medical Device Testing
• Clinical Services (Phase I-IV)

15. Advanced Clinical

Founded in 1994 and based out of Deerfield, Illinois, Advanced Clinical is a midsize and full-service CRO that helps sponsors with running clinical trials. The company employs more than 700 staff, and offers a wide variety of services across many therapeutic areas. Advanced Clinical has global representation in over 50 countries around the world.

Some clinical trial solutions offered by Advanced Clinical include:

• eTMF & Document Management
• Global Medical Services
• Quality & Validation

16. Pharm-Olam

Pharm-Olam is a leading midsize CRO with global headquarters located in Houston, Texas and its European headquarters in Bracknell, United Kingdom. The company employs more than 800 staff, and has 25 offices around the world, with a global coverage in more than 60 countries.

The company has therapeutic expertise in 5 areas, including Rare & Orphan Disease, Infectious Disease & Vaccine, Oncology-Hematology, Allergy and Autoimmune.

Some clinical trial solutions offered by Pharm-Olam include:

• Study Feasibility
• Site Activation
• Patient Recruitment
• Medical Affairs
• Compliance & Training
• Clinical Monitoring & Operations

17. Clinipace

Founded in 2003 and based out of Morrisville, North Carolina, Clinipace is a global midsize full-service CRO with a focus on solution customization for clinical trials. The company has a large global coverage in more than 50 countries, and has offices in North America, South America, Europe and Asia-Pacific regions.

Clinipace’s therapeutic focus areas include Oncology, Nephrology and Urology, Rare Disease, Gastroenterology and Women’s Health. The company also has complete therapeutic expertise in Infectious Disease & Vaccines, Cardiology, CNS, Immunology, and Respiratory.

Some clinical trial solutions offered by Clinipace include:

• Clinical Analytics
• Clinical Technology and Ecosystem
• Functional Service Partnership (FSP)
• Regulatory & Strategic Product Development

9 Fundamental Questions To Ask A Top CRO Company Before Signing The Contract

1. which services does the cro provide.

CROs offload a lot of operational tasks from trial sponsors, which can touch any component of clinical trial operations. From formulating an overall study strategy and implementing technologies to support the operational processes of the trial, to picking and identifying sites, and supporting patients during the trial, the range of clinical services offered by a CRO tends to be vast and inclusive of all the typical services and support you will require for running a successful clinical trial.

However, not all CROs are the same in their service offerings, or are able to offer the same depth of capability within a seemingly same clinical trial support process. For this reason it is important to understand exactly which kind of clinical services and support you are looking to receive from the prospective CRO when running your clinical trial.

While services such as clinical monitoring and clinical trial management are offered by the majority of CROs, the specific needs of each trial are unique, and for this reason it is important to first identify what will be the unique services your trial requires. Completing this internal analysis first will help you to understand the extent to which a potential CRO partner will be able to provide all of these services.

Some CROs specialize in specific clinical trial functions which the company may label as a “core services”, in which case this is a sign the company will have more expertise, experience, and will be set up in a way to maximize their capabilities in providing support for these services compared to other services that the CRO offers.

For example, a CRO may include patient recruitment as part of its “core services”, which implies that they are highly skilled in and have the necessary infrastructure to design and implement a high-quality patient recruitment strategy.

Clara Health CRO Support Services: At Clara Health our specialty services include technology-augmented digital and patient advocacy recruitment, as well as patient support via our signature patient recruitment platform, which we use to upgrade clinical trials and deliver results sponsors look for in their recruitment and retention campaigns.

At Clara, we work alongside CROs to supplement and support clinical trials with modern and personalized capabilities that CROs do not typically have the bandwidth, corporate structure or infrastructure to support.

If you would like to learn more about exactly how our platform can upgrade your unique trial, feel free to book a Free 30 Minute Consultation Session Here with one of our in-house experts.

2. What Related Experience Does The CRO Have?

It is helpful to ask the prospective CRO company if they have any relevant experience in running clinical trials that would be an asset in designing and running your study. Previous experience in a related therapeutic area or in running a trial with a similar design allows CROs to have a deeper understanding into potential opportunities and challenges, increasing the likelihood of your clinical study being successful.

For example, if a sponsor is planning to run a trial in oncology, for the purpose of site identification and selection it would be valuable to partner with a CRO vendor that has expertise in this area, as they likely already have a good understanding of which sites will lead to optimal results.

However, it is also important to consider all factors when selecting a CRO vendor and not to rely on therapeutic experience as the sole qualifier for whether or not a potential CRO is a fit for your trial. While previous experience is beneficial, some sponsors close themselves off from working with vendors that have not worked in their therapeutic area, which significantly limits options when choosing a CRO partner that is truly a good fit for their clinical study.

This can impact the end result of your clinical study, as sponsors that are not successful in choosing a CRO vendor that is the right overall fit may face difficulties if the needs of their clinical study aren’t being properly met.

Clara Health: We have worked to provide support for clinical trials across a wide range of therapeutic areas and trial designs. Our specialty is filling in the gaps that CROs traditionally did not have to think about, which include digital patient recruitment, patient advocacy recruitment, and technology-augmented patient support.

Additionally, we are constantly building our proprietary data and running tests in a variety of therapeutic areas. These research efforts allow us to have a detailed understanding of the expected level of difficulty when recruiting particular patient populations, as well as allow us to predict with accuracy which segments of the targeted population will be likely to qualify in a particular study.

3. What Are The Communication Workflows & Expectations For Performing And Delivering Contracted Services?

It is important that you clarify what the expectations for communication will be between your prospective CRO vendor and your internal teams, as you will most likely be working with the CRO of your choice for the entire duration of your clinical trial.

There are a vast variety of factors and success determinants for a clinical trial, which are continuously undergoing change as the study unfolds. For this reason, it is recommended that you work with a CRO that is proactive in their communication, so that you are kept up to date with information about important changes as your clinical trial progresses.

A vendor that is proactive rather than reactive in their communication and approach to dealing with arising issues is one of the most important qualities in CRO. Challenging situations will naturally arise, and the promptness with which they are taken care of will significantly impact your clinical trial’s degree of success. Therefore, seeking a vendor that is able to match the standard of communication that you as a sponsor would like to experience throughout the duration of your partnership is one of the most critical steps in determining which CRO is the right fit for your clinical trial.

We’ve included a few additional questions pertaining to the communication structure and reporting expectations that you can ask a prospective CRO vendor to determine the degree of fit in this particular category:

Communication Expectations:

• If we were to move forward with you, which of your team members will be our main point of contact?
• How available will you be outside of the scheduled meetings to address any of our concerns or additional requests?
• What will be the frequency at which update meetings will be conducted, and who will be present at those meetings?
• Which clinical study processes will be reported on, and what will be the workflow for how we will receive this information?
• What will be the cadence at which we will receive progress reports?
• Would we be able to access metrics electronically via an interactive dashboard, or will you send us formal reports?

Clara Health: At Clara Health, we directly interact and actively work with several key stakeholders involved in running a clinical trial, which includes sponsors, CROs, sites, and patients. This unique position allows us to have a centralized perspective which helps us to see all the moving parts of a clinical trial at the same time, which helps to identify issues and relay this vital information and insight back to the sponsor (or other appropriate stakeholders) in the shortest time possible.

The ability to access this perspective allows us to gather the most accurate, complete, and up-to-date information about how the clinical trial is unfolding, and quickly becomes very valuable to sponsors for their clinical trial.

As an example, we may receive feedback from patients about having an unsatisfactory experience with a particular study site. We are able to aggregate and analyze this information, and relay our findings back to the sponsor and the study site to improve the experience for other patients.

4. What Is The CRO’s Client Satisfaction Record?

It is a good practice to request information or metrics from the prospective CRO vendor that can point to the degree of satisfaction of their past clients. Prior to signing the contract, vendors will naturally do their best to uplift their image and future value to you during their sales conversations with you and your team. It can be tricky to get an objective understanding of what the partnership experience will actually entail, especially when there are multiple vendors fighting for your commitment.

We recommend that you ask the prospective vendor to provide success metrics regarding areas of clinical trial operations that are going to be important for your trial.

For example, you may be interested in learning about the vendor’s relationship to finances, in which case it will be useful to ask them about situations in which they went over the planned budget, and investigate into the reasons behind that. Alternatively you may be concerned about potential delays in timelines, in which case it would be helpful to learn about metrics regarding the CRO’s ability to meet timeline expectations.

You may also request to talk to the prospective CRO’s past clients, which will help you to gain insight into what the relationship was like and give you the opportunity to examine if the way in which the particular CRO manages its relationships and performs its services meets the expectations that you would have for your potential relationship and for your clinical trial.

Clara Health: At Clara Health, our relationships with our partners and with our patients are most important to us. In the unique position where we fit in the clinical trial process, we have the opportunity to directly co-create the clinical trial patient experience with a variety of stakeholders, including sponsors, sites, CROs, and patients.

Our company’s values and culture have been directed and developed to be such that the client and patient experience is at the top of priority for all of our internal teams, and we work to provide the best quality of care to all stakeholders.

We have many testimonials from every type of partner we’ve worked with which we can happily share with you.

5. How Do You Adapt When Encountering Challenges With Running A Clinical Trial?

It is inevitable that challenges and unforeseen changes will arise throughout the operational clinical trial process, and for this reason it is important to work with a CRO vendor that can provide you with evidence of their flexibility and ability to adapt to sudden changes.

The ideal CRO partner is one that is highly consultative throughout the entire process, and has an ability and the initiative to deal with challenges at their seed stage, prior to them turning into major obstacles for the success of your trial.

CROs naturally have a large reach, and there are a lot of different clinical trial mechanisms and processes that are under their control. They are able to monitor and respond to what is going on in every key link in the chain of the clinical trial operation.

It is reasonable to expect this level of oversight from a CRO, and additional questions that can help you gain insight into this include:

• What are some examples where the CRO was effective at monitoring the health of clinical trials they’ve helped operate in the past?
• How quickly does the CRO respond to challenges or opportunities for improving the clinical trial experience?
• How well does the CRO gather & process information from study sites, study teams, patients & the sponsor, and what are their typical data analysis workflows?

It is also recommended to speak to the prospective CROs past clients to help you gain insight into how well they respond and adapt to the naturally arising challenges in clinical trials.

Clara Health: While CROs do have a large reach within the clinical trial, no CRO has complete visibility into every clinical process. They are not typically set up to support full visibility, which can manifest as a potential threat to your clinical trial as it unfolds. This is especially true for parts of the clinical trial processes that CROs naturally do not specialize and often subcontract, such as clinical trial recruitment.

At Clara, we are in a unique position in relation to other key partners involved in operating the clinical trial. We are in direct and frequent contact with patients, CROs, study sites, study teams, and the sponsor, and have a very deep understanding of the patient pipeline. This allows us the unique ability to go very deep into specific parts of the recruitment chain and investigate what is working and what is not working.

In addition, Clara functions as a resource for all partners in the clinical trial. For example, we work directly with site teams to ensure that they have access to a 3rd party that they can relay their needs to and receive fast support in case there is anything they require that can improve the patient recruitment process.

6. Which Parts Of Operating The Clinical Trial Will You Be Outsourcing?

Since there are so many processes and mechanisms that go into operating a clinical trial, CROs will always outsource some parts of running and managing the study. While you can expect that the prospective CRO will subcontract some of the work, it is important to find out which exact parts the clinical study will be outsourced.

There are certain basic and key clinical processes (such as site selection) that CROs almost always help with, and if you find that these parts of your trial are going to be subcontracted to another company, it is recommended to find out why the CROs operations are set up this way and how this would impact the service you will receive.

Ultimately what matters to you as a partner and client is that the quality of service and care that you will receive will be up to standard, and meet what was promised and what you are expecting. While this trust is important after you have signed the contract, it is recommended that prior to entering into such a significant commitment that you have evidence and the conviction that the CRO of your choice is truly the right fit and will deliver the quality of service that was being discussed.

Since it is impossible to predict exactly what the quality of this relationship and services performed will actually be like in practice, it is recommended that you understand the details of what will be done for your trial and how. Investigating how the CRO outsources and subcontracts services for a clinical trial will help you to gain necessary insight that you would need to make the correct vendor selection decision.

Clara Health: At Clara, we maximize the effectiveness of the digital component across the entire digital & recruitment spectrum, which is added on top of the existing capabilities of the CROs and other vendors involved in operating your clinical trial. In addition, we offer services that augment the CROs efforts, which has the potential to significantly improve the patient experience, operations flows, recruitment and retention performance, which is so important in ensuring the success of a clinical trial.

For example, if a CRO wants to have a great site relationship, we are able to come in as a third party on behalf of the sponsor and CRO and act as a resource and additional support for sites.

In another example, If a sponsor wants to have great relationships with the patient community, Clara is able to come in on behalf of the sponsor and develop these relationships while being perceived more neutrally by the patient community.

7. Do You Have Experience Running International Trials?

If you are planning on operating an international clinical trial, it is recommended to work with a CRO that has extensive experience in this area. While many CROs will offer near-global coverage, the level of experience with specific geographic locations can significantly vary from one vendor to another.

It is important to work with a CRO that has experience running clinical trials in the specific countries and regions you are planning to conduct your research in. Being compliant with the local rules and regulations for clinical testing is a very complex process that requires existing understanding and familiarity in order to ensure logistical smoothness and to mitigate legal risks. In operating a clinical trial, there are a multitude of clinical services and processes, which can greatly vary across the many regions in which you can conduct clinical testing.

A CRO that is lacking experience in operating international trials or operating in particular regions where you plan on conducting research may not be able to meet your desired quality and agility expectations, and therefore may not be the right fit for your international clinical trial.

Clara Health: In the past, we have provided international patient recruitment and digitally-augmented trial support services for clinical trials in the EU, Canada, UK, Australia and South America.

Clara Health is fully compliant to operate international studies everywhere in the world, with the exception of Russia and China.

8. What Is Your Relationship With Patients?

Patient-centric approach to designing and operating a clinical trial is becoming more and more crucial in the clinical research space. The ability of a sponsor and their CRO partner to understand the needs and characteristics of their target patient community is a significant determinant of whether or not the study will be a success.

A sponsor that has close and authentic relationships with the patient community tends to have a deeper understanding of how to create the best clinical trial experience that will attract patients and keep their interest throughout the clinical trial.

In addition, strong relationships with patients allow sponsors and CROs to forecast recruitment and patient retention pipeline with much higher accuracy. This ability is critical for ensuring the success of the trial and mitigating the risk of low enrollment. After an understanding of the patient population is acquired, sponsors gain the necessary insight to design a clinical trial that is not only favorable to their research results, but is also practical and will result in the enrollment numbers they are looking for.

While many CROs have already recognized the importance of patient-centricity and evolved the ways in which they design and operate clinical trials, other CROs have not yet made such a pivot in their values. It is important to understand the degree of importance the prospective CRO places on creating a favorable patient experience, and what kind of infrastructure the company has to support it.

At Clara, we recommend choosing a CRO partner that is adapting to the patient-centric model which is becoming more and more important for running a successful clinical trial.

Clara Health: Since early stages of our development, we’ve had a dedicated patient advocacy team that has been integral in shaping our company’s vision and operations. We have built our entire platform and recruitment infrastructure around creating the best experience for patients. Our teams, corporate values, service offerings and company infrastructure all work in the service of the patient.

In addition, over the many years of being in business we have heavily invested in building authentic patient community relationships that span across a variety of therapeutic areas. This has given us a unique ability to receive feedback directly from patients that is genuine and authentic around marketing materials, strategy for patient recruitment, and other services that we build for specific trials.

This ability to build partnerships with the patient community in an authentic way gives us a very unique ability to engage with the patient community on behalf of a pharmaceutical company, allowing our sponsor & CRO partners the opportunity to start conversations with patients through our in-house patient advocacy team.

If you would like to learn how Clara can help you to build a strong & authentic relationship with your target patient community, get in touch with us and we’d be happy to share our capabilities and previous results with you as they relate to your current or upcoming clinical trial.

9. How Is The CRO Going To Utilize Patient Input For Developing The Trial?

In the initial stages of clinical trial design, sponsors often determine the ideal patient profiles that would help them to drive the most favorable research outcomes for their study. While it is important for the success of your trial to determine who your ideal patients are, very often these projections do not match up with what is viable in practice.

At Clara, we often encounter study protocols that are not set up realistically for successful recruitment to be possible.

Common mistakes that are made when determining trial eligibility criteria and trial design include:

• Overestimating the interest in the clinical trial from the target patient population
• A lack of patient focus in the trial design
• A lack of convenience for patients in their participation
• Complicated and/or inefficient study experience flows
• Crafting the eligibility criteria around the patient population that is most likely to lead to favorable study outcomes, without conducting sufficient research to more accurately estimate the recruitment and retention difficulty of the group for a particular study

It is natural for there to be a “push & pull” between the research ideal and the real world practicality. It is important to determine the correct balance between these two sides for your trial, as going too far in either direction will decrease the chance of your clinical study’s success.

The nature of the industry as it is right now is such that there is excess research idealization and not enough emphasis on patient centricity. This distorted orientation has resulted in many clinical trials being unsuccessful, negatively impacting sponsors, patients and the entire clinical trials industry.

The ideal CRO partner should help you make sure that your protocol design sets your study up for success. The CRO should be able to help you determine the proper balance between the research ideal and the real world practicality, and back up their findings with sufficient research and patient data that can project your trial being a success.

Clara Health: When formulating a recruitment and retention plan for our clients, we begin with conducting thorough research into the target trial patient population. This allows us to get a clear understanding of which recruitment channels will yield the best results and what kind of marketing materials will resonate with the prospective study participants.

To ensure accuracy and real-world applicability of our research, we consult and collaborate with our internal patient advocacy and patient support teams, as well as with our clients and patients representing the target trial patient profiles. We then tie our findings back with any existing proprietary data that we have in connection with the therapeutic area or the prospective target patient group.

Our unique position within the clinical recruitment chain gives us the presence and deep-rooted access needed to effectively tap into any of the three patient traffic sources: digital recruitment, offline recruitment, or patient advocacy recruitment.

Once a recruitment campaign has gone live, we constantly monitor, analyze and optimize our performance to make sure that the processes we have in place are as efficient as possible and drive the greatest results. In addition, we have the capability to layer in any traditional advertising (such as billboard ads) if requested by the study sponsor.

Top 15 Clinical Research Companies: Leaders in Medical Innovation

What’s on this page:

In the healthcare industry, the number of contract research organizations in the US has reached 2,823 in 2023. This marks a subtle but significant increase of 0.9% compared to the previous year.

This increase signals a vital trend: the growing complexity of finding the best clinical research companies in a crowded field. These organizations aren’t just businesses; they’re important in advancing medicine and developing drugs and therapies.

With such an important task, choosing the right company becomes essential. In this guide, we’ve looked closely at many companies along with their strengths and weaknesses and made a list of the top clinical research organizations. 

By the end, you’ll know which company is the best fit for your needs.

Quick List of Top 15 Clinical Research Companies

Here is a quick overview of the best companies of clinical research:

• IQVIA: Best for data-driven insights and advanced analytics in healthcare research.
• ICON: Best for comprehensive clinical development services and therapeutic expertise.
• Parexel: Best for global biopharmaceutical services, emphasizing regulatory and clinical trial excellence.
• Syneos Health: Best for integrated biopharmaceutical solutions and clinical-commercial capabilities.
• PPD: Best for drug development services with innovative, technology-enhanced trial strategies.
• Labcorp: Best for comprehensive clinical testing and diagnostics services with global reach.
• Medpace: Best for expertise in clinical research and regulatory affairs for pharmaceutical companies.
• Charles River Laboratories: Best for preclinical research and development services, including animal testing and research models.
• PRA Health Sciences: Best for clinical trial expertise and integrated solutions for biopharmaceutical development.
• AdvanCell: Best for innovative cell and tissue-based research solutions for life science industries.
• Dynata: Best for data-driven insights and market research services for informed decision-making.
• Covance: Best for end-to-end drug development solutions, from preclinical to post-marketing.
• MedNet: Best for technology solutions and eClinical platforms for streamlined clinical trials.
• Fisher Clinical Services Inc: Best for global logistics and supply chain services for clinical trial materials.
• Worldwide Clinical Trials: Best for specialized CRO offering personalized clinical research solutions.

3 Best Clinical Research Organizations: Comparison Chart

Here’s a comparison table to highlight the key features and differences among the best companies of clinical research. This table aims to provide a quick overview of each company’s unique strengths and areas of expertise in the pharmaceutical and healthcare research sector.

3 Top Clinical Research Organization List For Advanced Medical Discoveries

Now, we’ll explore the top clinical research organizations (CROs) dedicated to advancing medical discoveries. Let’s jump into the details of these exceptional organizations.

IQVIA is a global leader in clinical research and healthcare data analytics. They play a crucial role in the medical field by providing comprehensive data, advanced analytics, and expert insights. This helps pharmaceutical and healthcare companies make smarter, more effective decisions. 

Why is IQVIA among the best? Their strength lies in their vast database and advanced technology, which enable them to analyze complex healthcare data efficiently. This leads to a better understanding of diseases, more effective treatments, and faster drug development. 

IQVIA’s work is essential because it speeds up the process of bringing new medicines to the market, ultimately benefiting patients worldwide. In short, IQVIA is a key catalyst in advancing global healthcare.

About IQVIA

• Founding Team: Dennis Gillings
• Founding Year: 1982
• Company Size:   86,000

Features of IQVIA

IQVIA, a prominent player in the life sciences sector, is dedicated to advancing healthcare through connected intelligence. Here are some key features of IQVIA in the world of clinical research:

Innovative Clinical Development

IQVIA is reimagining clinical development by intelligently connecting data, technology, and analytics. This approach leads to faster decision-making and reduced risk, enabling the delivery of life-changing therapies more quickly.

Efficient Payment Systems for Clinical Trials 

They have simplified the process of paying sites involved in clinical trials. IQVIA offers the capability to make payments within 30 days, even in challenging locations. This significantly reduces the administrative burden of managing clinical trial payments by up to 90%.

Decentralized Trials Expertise

The company has conducted over 500 studies in more than 75 countries, covering over 30 indications using decentralized trial methodologies. This demonstrates their capability in managing complex, multinational clinical trials.

Global Reach and Impact

With a presence in various regions, including Australia, New Zealand, the Middle East, and Africa, IQVIA’s global footprint allows it to drive healthcare innovations worldwide.

AI and Technology Integration

The company is at the forefront of integrating AI and other technologies in healthcare. Their Healthcare-grade AI promises precision, speed, scale, trust, and reliability, essential for advancing health and improving patient outcomes.

• Extensive, reliable healthcare data enhances market research quality.
• Utilizes AI and machine learning for advanced healthcare insights.
• Specialized focus yields a deep understanding of healthcare dynamics.
• Broad international presence enables diverse and large-scale studies.
• Offers advanced tools for insightful healthcare data analysis.
• Advanced tools can be challenging to use without training.
• Handling sensitive health data raises privacy and security issues.

Our Review of IQVIA

IQVIA, a prominent player in the healthcare and life sciences industry, presents a mixed bag of strengths and weaknesses. On the positive side, we appreciate IQVIA’s extensive expertise in data analytics and healthcare consulting. 

Their comprehensive research and analysis have undoubtedly driven valuable insights and innovations in the sector. Moreover, their global presence allows for diverse perspectives and access to critical healthcare data.

However, we must also acknowledge some shortcomings. IQVIA’s services can be prohibitively expensive for smaller organizations, limiting accessibility. Additionally, the sheer volume of data can sometimes lead to information overload, making it challenging to extract actionable insights.

ICON is a prominent company in the field of clinical research, playing a significant role in advancing medical science. They specialize in designing and conducting clinical trials for new medicines and treatments. 

The work of ICON is crucial because they help determine the safety and effectiveness of these potential medical breakthroughs. They are considered one of the best in clinical research due to their high standards of accuracy, reliability, and ethical practices. 

ICON’s expertise ensures that the clinical trials they manage are conducted efficiently and effectively, leading to faster approval of new treatments. This directly impacts patient care, as it allows quicker access to new, potentially life-saving medicines. 

In essence, ICON’s contribution is vital in driving forward medical innovations.

• Founding Team: John Climax and Ronan Lambe
• Founding Year: 1990
• Company Size: 41,160

Features of ICON

Here are some of the key features of ICON in clinical research:

Diverse Clinical and Scientific Operations

ICON offers a wide range of clinical and scientific operations services, ensuring comprehensive support for various aspects of clinical trials. This includes everything from study design to execution and data analysis.

Decentralized Clinical Trial Solutions

They provide end-to-end services, operational models, and technology to deliver customized solutions for decentralized clinical trials. This approach is increasingly important in today’s clinical research landscape, offering flexibility and efficiency.

Specialized Therapeutic Areas

ICON has expertise across multiple therapeutic areas including cardiovascular, central nervous system, endocrine & metabolic disorders, infectious diseases, internal medicine & immunology, oncology, and more. This broad expertise allows them to handle a wide range of clinical research projects.

Innovative Solutions for Biotech

ICON provides full-service outsourcing and flexible support customized to the specific needs of biotech companies. This includes due diligence and asset valuation, which are critical for biotech firms navigating the complex landscape of drug development.

Advanced Medical Imaging Solutions

Their expert medical imaging solutions support all stages of clinical research, improving decision-making, increasing efficiency, and reducing trial costs.

• Decades of expertise ensure high-quality clinical research.
• Offers wide-reaching capabilities for multi-regional clinical studies.
• Deep understanding of global regulations enhances compliance and efficiency.
• Invests in new technologies for more efficient trial processes.
• Broad range of specialties contributes to comprehensive service offerings.
• Managing multi-regional trials can lead to logistical challenges.
• Rapid growth may strain resources and affect service quality.

Our Review of ICON

When we researched ICON, we found both commendable aspects and areas for improvement. On the positive side, we appreciate their commitment to clinical research and their global presence, which allows for diverse study options. Their experienced team and advanced technology contribute to reliable data collection and analysis.

However, there are some drawbacks to consider. We have noticed occasional delays in project timelines, which can be frustrating. Additionally, the cost of their services tends to be on the higher side, making it a potential barrier for smaller research endeavors.

Parexel is a globally recognized company in clinical research, known for its important role in developing new medical treatments. They are one of the biggest clinical research organizations. Parexel conducts clinical trials, crucial steps in testing the safety and effectiveness of new drugs. 

The work of Parexel is essential because it bridges the gap between medical research and the availability of new treatments to patients. One of the reasons they stand out as one of the best in this field is their rigorous approach to research. 

Their commitment to quality and their global network also enables diverse and large-scale studies, setting them apart from others in the field. These strengths allow Parexel to deliver reliable and valuable data, accelerating the process of bringing new, effective medicines to the market. 

Simply put, Parexel is a key player in transforming medical research into real-world health solutions.

About Parexel

• Founding Team: Josef von Rickenbach and Anne B. Sayigh
• Company Size: 18,900

Features of Parexel

Parexel, a global biopharmaceutical services organization, offers a range of features in clinical research. Here are some key aspects of their approach:

Patient-Centric Approach

Parexel emphasizes a patient-first strategy in their clinical trials. This approach results in deeper and more relevant insights for trial design and execution. This ensures that the trials are more aligned with patient needs and experiences.

Innovative Trial Designs

Parexel employs innovative trial designs to optimize trials for maximum impact. This includes advanced modeling and simulation to predict drug effects ahead of time, which can save time, money, and resources.

Regulatory Compliance and Market Access

Parexel designs studies and endpoints with market access in mind, ensuring that they satisfy global regulations. This approach helps in getting treatments to patients safely and quickly.

Patient Advocacy and Engagement

The company includes patient advocates in their council, using their experiences to improve trial designs. This inclusion demonstrates their commitment to understanding and incorporating patient perspectives in clinical research.

Focus on Speed and Precision

Parexel aims to design neuroscience trials with speed and precision, utilizing the right experts and specializations. This focus is crucial in delivering effective treatments on time.

• Provides advanced technology and analytics for efficient data management.
• Extensive network provides global insights with regional knowledge.
• Expertise in navigating complex regulatory environments worldwide.
• Broad experience across various therapeutic areas ensures versatile solutions.
• Focuses on patient engagement for more effective trial outcomes.
• Rapid expansion can lead to challenges in resource management.
• Concentration in specific areas could pose risks in market shifts.

Our Review of Parexel

Parexel is a notable player in the field of clinical research and pharmaceutical services. We’ve thoroughly analyzed their offerings and found both strengths and areas that need improvement.

On the positive side, Parexel excels in its commitment to innovation and technology. We appreciate their continuous efforts to simplify clinical trials and drug development processes, making them more efficient.

However, we also noticed some downsides. Communication with clients could be more transparent, with clearer updates on project progress. Additionally, there’s room for improvement in terms of ensuring consistency in service quality across different projects.

Other 12 Companies of Clinical Research

In the world of clinical research, beyond the well-known names, there are 12 other companies making significant contributions. Let’s explore their vital role in advancing healthcare.

1. Syneos Health

Syneos Health helps develop medicines by managing clinical trials for new drugs. They’re essential because they ensure medicines are safe and effective. Syneos Health stands out in clinical research for its comprehensive services and global reach, making drug development smoother and faster.

About Syneos Health

• Founding Team: Colin Shannon
• Founding Year: 1980
• Company Size: 28,000

PPD is a group that tests new drugs to see if they’re good and safe. This is crucial for getting new treatments to people. They stand out for their thorough research and global reach.

• Founding Team: Fred Eshelman 
• Founding Year: 1985
• Company Size: 40,000+3

Labcorp does important tests and research for health. They’re needed because they help find out if new treatments are good. They’re among the best for their big labs and fast results.

About Labcorp

• Founding Team: Matthew Benger
• Founding Year: 1978
• Company Size: 75,5000

Medpace focuses on making sure new health treatments are safe. This is key for better medicine. They’re a top choice because of their focus on quality and detail in research.

About Medpace

• Founding Team: August Troendle
• Founding Year: 1992
• Company Size: 5,400

5. Charles River Laboratories

Charles River Laboratories tests drugs and does research to help pets and people stay healthy. They’re essential for safe, new treatments. Their expertise makes them a leader in the field.

About Charles River Laboratories

• Founding Team: Henry Foster
• Founding Year: 1947
• Company Size: 21,400

6. PRA Health Science

PRA Health Science works on finding out if new medicines are safe. This helps everyone get better treatments. They’re known for their excellent research and care in studies.

About PRA Health Science

• Founding Year: 1976
• Company Size: 17,000+

7. AdvanCell

AdvanCell specializes in new treatments, checking if they’re safe and working. Their work is vital for progress in medicine. They’re recognized for their innovation in research.

About AdvanCell

• Founding Team: Andrew Adamovich

Dynata gathers data for health studies. They’re needed for understanding what works in healthcare. They’re a top name for their accurate and wide-reaching data collection.

About Dynata

• Founding Team: Mike Petrullo
• Founding Year: 1940
• Company Size: 5000-10000

Covance helps with drug tests and research to fight diseases. Their role is key for new treatments. They’re celebrated for their comprehensive services and global impact.

About Covance

• Founding Team: Fred Cummings
• Founding Year: 1981
• Company Size: 50,000

MedNet provides software for managing clinical trials. This helps in making research easier and faster. They’re among the best for their tech solutions in research.

About MedNet

• Founding Team: John “Rob” Robertson
• Founding Year: 1996
• Company Size: 51-200

11. Fisher Clinical Services Inc.

Fisher Clinical Services Inc. manages the logistics of clinical trials, ensuring that treatments are tested efficiently. Their work is crucial for the progress of medicine, and they are renowned for their reliability and global network.

About Fisher Clinical Services Inc.

• Founding Team: John Pickering
• Founding Year: 1989

12. Worldwide Clinical Trials

Worldwide Clinical Trials conducts essential research to evaluate new medical treatments. Their work is critical for advancing healthcare. They are distinguished by their global expertise and commitment to innovation in clinical research.

About Worldwide Clinical Trials

• Founding Team: Neal Cutler
• Founding Year: 1986
• Company Size: 3,147

What To Consider When Choosing the Best Clinical Research Companies?

Choosing the right clinical research company (CRC) is crucial for the success of any clinical trial. Here’s a detailed guide on what to consider:

Expertise and Specialization

Always ensure the CRC has expertise in your specific therapeutic area. Companies with experience in similar drug trials or medical devices can better navigate the complexities of your project.

Regulatory Compliance

The CRC must adhere to regulatory guidelines like FDA (US) , EMA (Europe), and others. Check their track record in meeting these standards to avoid compliance issues.

Reputation and Track Record

You should research the company’s history. Look for testimonials, case studies, and reviews from past clients. A company with a strong reputation is likely to deliver quality results.

Project Management Capabilities

Effective project management is key. Assess their ability to manage timelines, budgets, and communication. A CRC that provides transparent, regular updates is preferable.

Patient Recruitment Strategies

Patient recruitment can be challenging. Evaluate their strategies for participant recruitment and retention. Consider their demographic reach and methods for ensuring a diverse participant pool.

Data Management and Analysis

The CRC should have strong systems for data collection, management, and analysis. Ask about their use of Electronic Data Capture (EDC) systems and how they handle data security and confidentiality.

Cost and Financial Terms

Get a clear understanding of the cost structure. Consider the value for money rather than just the lowest cost. Ensure there are no hidden fees and clarify what is included in the quoted price.

How Heartbeat AI Can Help You Get the Best List of Clinical Research Organizations?

Heartbeat AI, with its advanced features, can significantly assist in identifying the best list of clinical research organizations (CROs). Here’s how its various features contribute to this process:

Data Analysis and Processing

Heartbeat AI excels in analyzing vast amounts of data. When it comes to selecting CROs, it can process and analyze information from numerous sources, including past performance records, clinical trial reports, and regulatory compliance data. This thorough analysis helps in identifying CROs with a proven track record of success and reliability.

Machine Learning Algorithms

These algorithms enable Heartbeat AI to learn from historical data and improve its recommendations over time. By understanding trends and patterns in the successful execution of clinical trials, it can better predict which CROs are likely to meet your specific needs.

Predictive Analytics

Heartbeat AI uses predictive models to forecast future trends and outcomes based on historical data. This can be invaluable in predicting the success rate of CROs in upcoming projects, thus aiding in making more informed choices.

Customization and Personalization

The AI can be customized to your specific requirements. If you’re focusing on a specific therapeutic area or clinical trial phase, Heartbeat AI can prioritize specialized CROs in these fields.

Real-time Data Updates

The healthcare and pharmaceutical landscapes are constantly changing. Heartbeat AI’s ability to integrate and analyze real-time data ensures that the recommendations are based on the most current information available.

Integration with External Databases

Heartbeat AI can integrate with various external databases and platforms. This enables it to pull in comprehensive information about CROs from diverse sources, enhancing the accuracy of its recommendations.

Claim $500 of Free Data  

Summing up, we’ve explored the best clinical research companies, diving into their features, strengths, weaknesses, and more. Clinical research is vital in healthcare; it’s key for advancing medical knowledge and developing new treatments. 

With this guide, you’re equipped to find the right clinical research company that meets your specific needs. Whether it’s for innovative therapies, drug development, or medical advancements, choosing the right partner is crucial. This guide serves as a valuable resource to help you make an informed decision in the complex world of clinical research.

Frequently Asked Question

What services do companies of clinical research offer.

Clinical research organizations offer a wide range of services, including protocol development, patient recruitment, data collection and analysis, regulatory compliance, and more.

What is the role of a clinical research coordinator?

A clinical research coordinator is responsible for managing various aspects of a clinical trial, including patient recruitment, data collection, and ensuring compliance with protocols.

What is informed consent in clinical research?

Informed consent is the process by which participants in a clinical trial are fully informed about the study’s purpose, risks, and benefits. They voluntarily agree to participate based on this information.

1-888-664-9690

[email protected]

• Corporate Brochure
• Case Studies
• Testimonials
• Press Release
• Vascular Surgeons Email List
• Pathologists Email List
• Gastroenterologist Email List
• Chiropractors Email List
• Anesthesiologists Email List
• Plastic Surgeons Email List
• Pediatricians Email List
• Geriatricians Email List
• General Surgeons Email List
• Diabetes Specialist Email List
• Allergist / Immunologist Email List
• Arthritis Specialists Email List
• Cardiologist Email Lists
• Dermatologist Email List
• Neurologists Email List
• Orthopedic Surgeons Email List
• Urologists Email List
• Podiatrist Email List
• Dermatopathologist Email List
• Hematologists Email List
• Pulmonologists Email List
• Nephrologists Email List
• Oncologist Email List
• Rheumatologist Email List
• Radiologist Email List
• Optometrist Email List
• Ophthalmologist Email List
• Acupuncturist Email List
• Optician Email List
• Neonatologist Email List
• Neuropathologist Email List
• Hepatologist Email List
• Traumatologist Email List
• Gynecologists Email List
• Psychiatrists Email List
• Endocrinologist Email List
• Hygienists Email List
• Primary Care Physicians‎ Email List
• General Practitioners Email List
• Osteopathic Physicians Email List
• Emergency Physicians Email List
• Bariatric Physician Email List
• Family Medicine Specialist Email List
• Epidemiologist Email List
• Clinical Lipidologist Email List
• Registered Dieticians Email List
• Psychologists Email List
• Neurosurgeon Email List
• Nutritionists Email List
• Audiologist Email List
• Hypnotists Email List
• ENT Specialists Email List
• Sleep Medicine Specialists Email List
• Sports Medicine Physician Email List
• Physiatrists Email List
• Physician Assistants (PAs) Email List
• Athletic Trainers (ATs) Email List
• Cosmetologists Email List
• Pediatric Allergists Email List
• Naturopathic Doctors Email List
• Veterinarian Email Lists
• Phlebotomists Email List
• Pediatric Radiologists Email List
• AMA Physicians Email List
• Paramedics and EMTs Email List
• Pediatric Neurologist Email List
• Preventive Medicine Specialist Email List
• Reproductive Endocrinologist Email List
• Interventional Cardiologists Email List
• Nuclear Medicine Specialist Email List
• Infectious Disease Specialist Email List
• Radiation Oncologists Email List
• Internal Medicine Specialist Email List
• Mental Health Specialists/Professionals Email List
• Addiction Medicine Specialist Email List
• Aerospace Medicine Physicians Email List
• Hematology & Oncology Specialist Email List
• Medical Geneticist Email List
• Addiction Psychiatrist Email List
• Physical Medicine Rehabilitation Email List
• Cardiac Care Nurses Email List
• Critical Care Nurses Email List
• Emergency Nurses Email List
• Geriatric Nurses Email List
• Home Healthcare Nurses Email List
• Military Nurses Email List
• Nurse Anesthetists Email List
• Nurse Practitioners Email List
• Registered Nurses Email List and Mailing List
• Neurology Nurses Email List
• Orthopedic Nurses Email List
• Occupational Health Nurses Email List
• Pediatric Nurse Practitioners Email List
• Dermatology Nurses Email List
• Perioperative Nurses Email List
• Midwife Nurses Email List
• Family Nurse Practitioners (FNP) Email List
• Public Health Nurses (PHNs) Email List
• Endocrinology Nurses Email List
• Ambulatory Care Nurses Email List
• Women’s Health Nurse Practitioners Email List
• Adolescent Medicine Nurses Email List
• Reproductive Health Nurses Email List
• Transplant Nurses Email List
• Dialysis Nurses Email List
• Allergy / Immunology Nurses Email List
• Family Planning Nurses Email List
• ENT Nurse Practitioners Email List
• HIV/AIDS Nurses Email List
• Community Health Nurses Email List
• School Nurses Email List
• Student Nurses Email List
• Nurse Manager Email List
• Oncology Nurses Email List
• Child Psychiatric Nurses Email List
• IV Certification Nurses Email List
• Licensed Practical Nurses Email List
• Licensed Vocational Nurses Email List
• Clinical Nurse Specialist Email List
• Acute Care Nurse Practitioners Email List
• Office Based Nurses Email List
• Certified Registered Nurse Anesthetist Email List
• Certified Nursing Assistants Email List
• Psychiatric-Mental Health Nurse Practitioners Email List
• Adult Care Nurse Practitioner Email List
• Registered Pharmacist Email List
• Hospital Druggist Email List
• Druggist Email List
• Community Pharmacists Email List
• Pharmacist Clinicians (PhC) Email List
• Ambulatory Care Pharmacists Email List
• Pharmaceutical Email & Mailing List
• Prosthodontists Email List
• Periodontist Email List
• Endodontists Email List
• Pediatric Dentists Email List
• Orthodontist Email List
• Oral Pathologists Email List
• Denturist Email List
• ADA Dentists Email List
• Dental Hygienist Specialists Email List
• Oral and Maxillofacial Radiologists Email List
• Oral and Maxillofacial Surgeons Email List
• Subacute Care Centers Email List
• Cancer Centers and Services Email List
• Ambulatory Surgery Centers Email List
• Diagnostic Imaging Centers Email List
• Urgent Care Centers Email List
• Trauma Centers Email List
• Nursing Homes Email List
• Nursing Home Administrators Email List
• Hospital Email List
• Assisted Living Facilities Email List
• Medical Institutions Email List
• X-Ray Laboratories Email List
• Primary Care Centers Email List
• Dental Clinics Email List
• Blood Bank Centers Email List
• Dental Laboratories Email List
• Clinics Email List
• Physical Fitness Facilities Email List
• Med Spa Email List
• Dental Equipment / Supplies Manufacturers Email List
• Biomedical Equipment Manufacturers Email List
• Electro-Medical Equipment Manufacturers Email List
• X-Ray Apparatus and Tubes Manufacturers Email List
• Ophthalmic Goods Manufacturers Email List
• Surgical Appliances Manufacturers Email List
• Surgical / Medical Instruments Manufacturers Email List
• Neuromodulation Devices Manufacturers Email List
• Cardiovascular Devices Manufacturers Email List
• Therapeutic Devices Manufacturers Email List
• Spine Devices Manufacturers Email List
• Laboratory Equipment and Supplies Email List
• Hospital Equipment and Supplies Email List

The Top 10 Clinical Research Companies in the USA

• Dec 02, 2022
• Posted By: admin

To bring effective medicines and Innovations in healthcare industry , a Clinical Research Organization or Contract Research Organization (CRO) are a must for the Biotech, Medtech, and pharma industries. A CRO offers comprehensive support to their efforts to test, examine, refine and market the latest medicines and devices that help in improving Healthcare Industry.

In 2022, the global clinical research market stands at $63.6 billion , and by 2027, it is expected to reach around an exciting amount of 115.1 billion with a CAGR of 11.0% from 2022 to 2027.

This growth is powered by an increase in R&D activities and expenditures and a significant rise in clinical trials owing to the need for innovations in healthcare. For that reason, it is also essential to be aware of the most prominent global research organizations that offer vital support with their specialized clinical trial solutions. This post will walk you through the ten big Clinical Research Companies In USA . So, let’s begin:

• Founded: 1982
• Headquarters: Durham, North Carolina
• Annual Revenue : $13.87B
• Employee Size: 88,000

IQVIA is one of the largest Clinical Research companies in the world that works profusely to enhance healthcare by integrating the study of human science with discoveries in technology and data science to improve understanding of human health and provide better and quicker care.

It helps pharma companies, along with other medical organizations, to innovate and maximize positive outcomes. In addition to clinical research and development, IQVIA has also developed analytics and technology solutions to aid the medical sector in commercializing products and enhancing customer engagement.

Some clinical trial solutions given by IQVIA are as follows:

• Site identification & Selection
• Help with protocol design
• Design of clinical trial phase -1
• Investigation and improvements of the clinical trial in phases 2 and 3
• Accessibility to global laboratories

2. Pharmaceutical Product Development (PPD)

• Founded: 1985
• Headquarters: Wilmington, North Carolina
• Annual Revenue: $65.0M
• Employee Size: 24,000

PPD, also known as Pharmaceutical Product Development, is an extensive research organization headquartered in the United States but has a widespread global presence.

The company directs its attention to three prime areas: pharma development, lifecycle management services, and laboratory. Besides, it has clients and partners covering various sectors, including pharmaceutical companies, biotech firms, medical device manufacturers, and government or academic organizations. 

Some clinical trials offered by PPD include:

• Early Development
• Consulting and Product Development
• PPD Biotech
• The site and patient-centered Solutions
• Clinical Development

• Headquarters: Waltham, Massachusetts
• Annual Revenue: $3B
• Employee Size: 18,000

Parexel is another important name in the list of Clinical Research Companies In USA that specializes on behalf of its pharmaceutical partners in carrying out clinical studies to boost and make certain that the medicine approval process takes place smoothly. It has a wide range of offerings that spreads across every type of clinical trial service to help sponsors work on creating successful trials.

Some of the clinical trial solutions which Paraxel offers:

• Management of clinical data
• Medical writing
• Regulatory affairs consulting
• Design and development of clinical trials at all phases
• Clinical supply chain management

With pride, the company operates in over 50 countries and owns over 95% of the top 200 selling biopharmaceuticals in today’s market.

4. PRA Health Services

• Founded: 1976
• Headquarters: Raleigh, North Carolina
• Annual Revenue: $64.3M
• Employee Size: 16,400

PRA Health Sciences is a contract research organization that provides coverage in more than 90 countries worldwide. It principally centers on contributing therapeutic and operational expertise through integrated applications and supplying local expertise in particular areas. Besides, it works in the early and end stages of clinical trial procedures and the domains of strategy, consultancy, technology, and bio-analytics.

Moreover, it works hard to speed up medicine development operations to introduce better and more effective medicine sooner in the market.

Let’s take a peek at the PRA Health Sciences clinical trial solutions:

• Onsite support services
• Personalized solutions for Biotech
• Clinical Diagnostics
• Site Commercial Solutions
• Protocol Consultation and Study Design
• PRA’s Laboratories for Medicine Development

5. Syneos Heath

• Founded: 1999
• Headquarters: Morrisville, North Carolina
• Annual Revenue: $5,213M
• Employee Size: 28,000

With the merger of inVentiv Health and INC Research, Syneos Health was created that combines every discipline involved in bringing new therapies or products to market, from clinical research to consulting and commercialization.

Though it provides clinical development services spanning all stages, it primarily owns a specialization in helping healthcare organizations with the late stages of clinical trials. Moreover, its commercial solutions cover communication, consulting, and medication adherence.

The clinical trial solutions it offers include:

• Early phase
• Decentralized clinical trial solutions
• Clinical data management
• Pharmaceutical
• Medical Device Diagnostics

• Founded: 1978
• Headquarters: Burlington, North Carolina
• Annual Revenue: $16.1B
• Employee Size: 70,000

Laboratory Corporation of America, or LabCorp, focuses on offering extensive clinical laboratory solutions and end-to-end medication and diagnostic development and commercialization.

The company develops special testing operations such as HIV genotyping, oncology testing, phenotyping, clinical trials, and diagnostic genetics. Moreover, its services are spread through care organizations, hospitals, government agencies, pharmaceutical companies, and physicians.

Some clinical trial solutions provided by LabCorp are:

• Preclinical Services
• Post-Marketing Solutions
• Medical Devices
• Clinical Trial Laboratory Services
• Clinical Trials
• Data & Technology

7. Charles River Lab

• Founded: 1947
• Headquarters: Wilmington, Massachusetts
• Annual Revenue: $690.4M
• Employee Size: 20,000

Charles River laboratories proudly span its capabilities throughout the medical R&D process from basic research to pre-clinical stage testing, manufacturing and commercialization within two significant services: Good Laboratory Practice (GLP) and non-GLP. It offers precise support to help its partners advance their research and efforts to introduce effective medicines in the market.

The company further serves biotechnology and pharmaceutical companies, hospitals, government agencies, and academic institutions.

Some of the clinical development solutions it offers include:

• Bioanalysis
• Clinical Kitting services
• Data management
• Quality control
• Stability testing

8. Fisher Clinical Services

• Founded: 1989
• Headquarters: Center Valley, Philadelphia
• Annual Revenue: $17B
• Employee Size: 50,000

Fisher Clinical Services is a part of Thermo Fisher Scientific that has been for over 20 years in the business of supply chain management. It focuses exclusively on working with distribution and packaging requirements of clinical trials happening around the globe.

The company is committed to providing high-value products which adhere to the standard of pharmaceutical companies and is reliable, sustainable and perform well.

Some of the clinical trial solutions offered by Fisher Clinical Services are:

• Cell & Gene Therapy
• Clinical Label Services
• Clinical Supply Optimization services
• Direct to patient
• Biologistics management

9. Medpace Holdings

• Founded: 1992
• Headquarters: Cincinnati, Ohio
• Revenue: $1B
• Employee Size: 1,001-5,000

Medpace offers support services for phases one to five of clinical trials for biotechnology, pharmaceutical companies, and medical device industries. It is a scientifically-driven organization that offers full service and helps industries make key differences with their contributions to the healthcare sector.

Some of the clinical research solutions that you receive from Medpace are:

• Medical Writing
• Quality Assurance
• Clinical Monitoring
• Clinical Trial Management
• Risk-based Monitoring
• Regulatory Affairs
• Biostatistics and Data sciences

10. Advanced Clinical

• Founded: 1994
• Headquartered: Deerfield, Illinois
• Annual Revenue: $106M
• Employee Size: 501-1,000

A mid-size and full-service Clinical Research organization that helps sponsors run clinical trials and offers various solutions across therapeutic fields. It allows clients to secure better outcomes through candid discussions, conversations, foresight, and innovative solutions.

The company works hard to improve every life touched by clinical research. As such, some clinical solutions provided by Advanced Clinical are:

• Project management
• Clinical monitoring
• eTMF and document management
• Quality & Validation

The Bottom Line

There you have it – the best Clinical Research Companies In USA to get support from while working on new medicine or medical devices.

CROs play a critical role in the pharmaceutical, biotech, and medical device industries to manage and lead their clinical trials now more than ever due to rapidly rising prices, regulations, and tighter deadlines. Also pharmaceutical companies approaching Clinical Research Organizations for their R&D activities to stay competitive, flexible, and profitable against all odds.

The leading clinical research organizations

We've ranked the top 10 clinical research organizations.

UNBIASED RESEARCH RANKINGS

HIGHEST STANDARDS REQUIRED

PROPRIETARY CRITERIA SYSTEM

What people are saying: #Passionate #Innovative #Dedicated

Parexel is a clinical research organization that provides biopharmaceutical services and solutions. They have expertise in clinical development, translational medicine, and early phase research. Parexel has over 10,000 employees in 50 countries. Parexel has been recognized by Frost & Sullivan with the 2022 Global Customer Value Leadership Award. Parexel's services are designed to help pharmaceutical and medical device companies bring new treatments and therapies to market. Parexel's clinical development services include phase I-IV clinical trials, biostatistics, clinical data management, clinical supply chain management, decentralized clinical trials, medical monitoring and consulting, medical writing, patient sensors, pharmacovigilance, and risk-based quality management. The company's expanded access services provide access to investigational treatments for patients with serious or life-threatening conditions who are not eligible for clinical trials. Their outsourcing services include functional services provider and strategic partnerships.Parexel's team of experts has the knowledge and experience to help bring new treatments and therapies to market.

IQVIA clinical research

What people are saying: #Involved #ResearchOriented #PatientFriendly

IQVIA clinical research is a company that provides information on clinical trials and patient communities. They also have a section on their website where you can register for updates on new clinical trials and community events. The company has a strong focus on helping to expand meningitis research and they are currently recruiting participants for a new clinical study. They are also seeking volunteers to help advance respiratory syncytial virus (RSV) research. In addition, they are working on a clinical study to help find a way to speed up recovery from COVID-19 and reduce the need for hospital care. Overall, IQVIA clinical research is a company that is heavily involved in a variety of research studies in order to help improve medical treatments and find new cures for diseases.

What people are saying: #Comprehensive #Quality #Dedicated

Medpace is a full-service CRO that provides support for drug, biologic, and medical device programs. They have a global reach and offer services including clinical monitoring, biostatistics and data sciences, regulatory affairs, and more. They are dedicated to making the complex seamless and strive to provide the highest level of quality and service.

Syneos Health

What people are saying: #Quality #Experienced #Committed

Syneos Health is a biopharmaceutical company that provides solutions for clinical development, commercialization, and consulting. The company has a wide range of services and products that cater to the needs of their clients. They have a team of experienced professionals that work together to provide the best possible service. The company is committed to providing the highest quality of care to their clients and patients. They have a wide range of experience in different therapeutic areas, which allows them to provide the best possible care to their patients.

Charles River Laboratories

What people are saying: #Experienced #Dedicated #Successful

Charles River Laboratories is one of the top clinical research organizations in the United States. They offer a variety of services to help pharmaceutical and biotechnology companies develop and commercialize their products. These services include preclinical research, clinical research, and manufacturing support. Charles River Laboratories has a long history of helping companies develop new drugs and therapies. They have a team of experienced scientists and clinicians who are dedicated to helping their clients succeed. They offer a wide range of services, from preclinical research to clinical research to manufacturing support. They have a proven track record of success, and they are a trusted partner for many companies. If you're looking for a top clinical research organization to help you develop and commercialize your products, Charles River Laboratories is a great choice.

What people are saying: #Transparent #Innovative #Unique

Caidya is a leading clinical research organization that provides full-service support and vast therapeutic expertise to its clients. The company has a personalized approach to clinical research and offers a unique combination of global experience and knowledge sharing. Caidya's clinical research services are designed to connect you with unrivaled access to specialist knowledge and resources. The company's cutting-edge clinical technology integrates effortlessly to create an ecosystem that meets the specific needs of your study. Caidya's Clarity platform synthesizes data from different systems to create a near real-time view of your trial. This holistic view allows integrated teams within Caidya to transparently share information and data, generating insights to inform your decisions.

What people are saying: #Healthy #Helpful #Compensated

ICON is a clinical research company that is looking for healthy volunteers to participate in studies. The company has locations in Lenexa, KS and Salt Lake City, UT. Participation in a study includes 1 screening visit, 1 stay of 11 nights (12 days) and 1 follow-up visit. Compensation for participation is up to $6400. ICON is a great opportunity for people who want to make some extra money and help out with medical research.

What people are saying: #Trusted #Innovative #Leading

PPD is one of the top clinical research organizations in the United States. They offer a wide range of services, from drug development to clinical trials. They have a team of experienced professionals who are dedicated to helping their clients succeed.

CTI Clinical Trial and Consulting

What people are saying: #Experienced #FullService #Comprehensive

CTI Clinical Trial and Consulting is a full-service CRO that specializes in clinical research and consulting services. They offer a wide range of services including regulatory development, clinical project management, clinical monitoring, biometrics, quality assurance, and real world evidence. They also have a research center where you can participate in clinical trials. The range of services offered by CTI Clinical Trial and Consulting is excellent. They seem to be a one-stop shop for all your clinical research needs. We also like that they have a research center where you can participate in clinical trials. This is a great way to get involved in the latest medical research and to potentially help develop new treatments for various diseases.

Advanced Clinical

What people are saying: #Comprehensive #CustomerFocused #AwardWinning

Advanced Clinical is a top-tier contract research organization that has provided clinical research services to the pharmaceutical and biotech industry for many years. Their global reach and comprehensive solutions make them a perfect partner for companies launching clinical trials. Their focus on satisfaction and customer service is evident in their high employee retention rate and repeat business rate. Their award-winning culture and commitment to excellence make them a great choice for anyone looking for a clinical research partner.

Clinical Research Organizations: What should you be looking for?

The website's mission is to provide accurate, timely, and reliable rankings of clinical research organizations. We aim to provide users with a comprehensive and up-to-date list of the top clinical research organizations so they can make informed decisions about which ones to use. We also provide detailed descriptions of each organization so users can learn more about their work.

Are Clinical Research Organizations (CRO) worth it?

Yes, it is worth hiring clinical research organizations. Here are three reasons why: 1. Clinical research organizations have the experience and expertise to conduct clinical trials effectively. They know how to design trials that meet regulatory requirements, recruit patients, and collect data. 2. Clinical research organizations can help you save time and money. They can manage all aspects of the clinical trial process, so you can focus on other aspects of your business. 3. Clinical research organizations can provide valuable insights into the clinical trial process. They can help you understand the data, identify potential problems, and make decisions about the best course of action.

What to look for when hiring Clinical Research Organizations (CROs)?

Using a Clinical Research Organizations can be a great way to get the medical care that you need. However, there are a lot of questions that you may have about using one. That is why we have provided FAQs for customers interested in using a Clinical Research Organizations. We want to make sure that you have all the information that you need so that you can make the best decision for your medical care.

What are the specific research needs of your organization?

The first step in finding the right Clinical Research Organization (CRO) for your needs is to identify the specific research needs of your organization. These needs will vary depending on the type of research you are conducting, the size and scope of your project, and your budget. Once you have a clear understanding of your research needs, you can begin to research different CROs and compare their services. When considering a CRO, it is important to look at their experience in conducting the type of research you need. Make sure to ask about their success rates and customer satisfaction levels. You should also inquire about their pricing structures and what type of services are included in their fees. It is also important to consider the size of the CRO and their ability to handle your project. Make sure they have the staff and resources necessary to complete your project on time and within budget. Finally, you should also consider the location of the CRO. If your project requires frequent travel, you may want to choose a CRO that is located near your site. If you are conducting research that requires special expertise, you may want to choose a CRO that is located near a research university or hospital.

What is the size and scope of your organization?

Next, you need to understand the size and scope of your organization, and thereby understand the size and scope of the CRO you need to hire. Is the CRO a large, full-service clinical research organization that offers a wide range of services to its clients? Does the CRO have a global reach and is it able to provide its services to clients in a number of different countries? Does the CRO have a large team of experienced and qualified staff who are able to provide a high level of service to its clients? Is the CRO accredited by a number of different bodies and is it able to offer its services to a wide range of clients?

What are the your clinical research priorities?

Finally, you need to understand your organization's clinical research priorities. Are they to develop new treatments for diseases and conditions, to improve the safety and efficacy of existing treatments, or to increase our understanding of the underlying causes of disease? This will help you select a CRO that aligns with your needs.

Key Takeaways about Clinical Research Organizations

When choosing a clinical research organization, it is important to consider the size of the organization, its focus, its location, and its resources. The best clinical research organizations are those that are able to provide the most comprehensive services and the most experienced staff. They should also be able to offer the latest technology and facilities. Top Clinical Research Organizations is dedicated to providing objective rankings of clinical research organizations. We believe that our rankings will help you choose the best organization for your needs. We are committed to providing the most accurate and up-to-date information possible.

Frequently Asked Questions

What is a clinical research organization (cro).

A clinical research organization (CRO) is a company that provides services to pharmaceutical and biotechnology companies to help them outsource and conduct clinical trials. A CRO manages all aspects of a clinical trial, from start to finish, and works with a variety of stakeholders, including investigators, research sites, and patients.

CROs are an important part of the drug development process, as they provide expertise and resources that allow companies to efficiently and effectively conduct clinical trials. Without CROs, many new drugs and treatments would not be possible.

What services do CROs provide?

CROs provide a variety of services to support clinical research, including study design, data management and analysis, regulatory affairs support, and clinical trial management. CROs also provide a variety of other services, such as market research, project management, and training.

What are the benefits of working with a CRO?

There are many benefits of working with a clinical research organization (CRO). CROs can provide expertise and resources that Sponsors may not have internally, and can therefore help to increase the efficiency and quality of clinical trials. In addition, working with a CRO can help to reduce costs associated with clinical trials. CROs also have experience working with a variety of different Sponsors, and can therefore provide valuable insights and perspectives.

What are the risks of working with a CRO?

The risks of working with a CRO include the potential for conflicts of interest, the potential for data manipulation, and the potential for data fraud.

How do CROs ensure the safety of trial participants?

There are a number of ways that clinical research organizations (CROs) ensure the safety of trial participants.

First, CROs typically have staff members who are responsible for monitoring the safety of participants throughout the course of a study. These staff members may be nurses, doctors, or other health care professionals. They typically have experience in managing clinical trials and are familiar with the potential risks and side effects of the drugs or treatments being studied.

Second, CROs typically have established procedures for reporting and managing adverse events. These procedures ensure that any potential safety concerns are promptly identified and addressed.

Third, CROs typically work closely with the sponsor of a clinical trial (usually a pharmaceutical company) to ensure that the sponsor is aware of any safety concerns that arise during the course of the trial. The sponsor is ultimately responsible for the safety of the participants, and the CRO ensures that the sponsor is kept informed of any safety issues that arise.

Fourth, CROs typically conduct regular audits of their clinical trials to ensure that they are being conducted in accordance with good clinical practices and that the rights and safety of participants are being protected.

Finally, CROs typically have insurance policies in place that protect participants in case of any unforeseen events that may occur during the course of a trial.

Overall, the procedures and policies that CROs have in place help to ensure the safety of participants in clinical trials.

How do CROs ensure the quality of data collected during a clinical trial?

CROs ensure the quality of data collected during a clinical trial by following Good Clinical Practices (GCPs).

GCPs are a set of international standards that ensure the quality, safety, and integrity of data collected during a clinical trial. All CROs must adhere to these standards in order to conduct clinical trials.

What happens if a CRO is unable to meet its contractual obligations?

If a CRO is unable to meet its contractual obligations, it may be required to pay damages to the sponsor. The sponsor may also be able to terminate the contract and seek a new CRO.

What is the role of the sponsor in a clinical trial?

What are the responsibilities of the principal investigator in a clinical trial.

The principal investigator (PI) is responsible for the overall conduct of the clinical trial. This includes ensuring that the trial is conducted in accordance with the protocol, applicable regulations, and standard operating procedures. The PI is also responsible for the safety of the trial participants and for ensuring that the data collected are of high quality.

The PI works with the sponsor, other investigators, and the research team to ensure that the clinical trial is carried out correctly and that the data collected are of high quality. The PI is also responsible for the safety of the trial participants.

How are clinical trial sites selected?

When selecting a clinical trial site, sponsors and contract research organizations (CROs) consider a number of factors.

The most important factor is usually the site’s experience and success in conducting similar trials.

Other important factors can include the site’s patient population, geographic location, and facilities.

How are clinical trial subjects recruited?

There are a number of ways that clinical trial subjects can be recruited. One common method is through advertisements in newspapers or other media outlets. Another common method is through word-of-mouth, where people who know about the clinical trial spread the word to others who might be interested. Additionally, clinical trial subjects can be recruited through doctors or other medical professionals, as well as through patient advocacy groups.

How is informed consent obtained from clinical trial subjects?

Informed consent is obtained from clinical trial subjects by providing them with information about the trial in a way that is easy for them to understand. This includes information about the purpose of the trial, the procedures that will be used, the risks and benefits of participating, and their right to withdraw from the trial at any time. Informed consent is not simply a form that subjects must sign; it is a process of communication between the researcher and the subject that should ensure that the subject understands the trial and is willing to participate.

• Reach Our Healthcare List Expert   +1 (786) 408 5757
• Browse Data Cards
• GET A QUOTE

The Top Players in Clinical Research: A Review of the Leading Companies

Top 10 leading clinical research companies in the usa.

The landscape of drug discovery and development is intricate, demanding significant resources at each stage of the process. As pharmaceutical companies strive to bring groundbreaking therapies to market, they increasingly rely on the expertise of Contract Research Organizations (CROs). These organizations play a vital role in supporting drug manufacturers throughout the entire drug development journey, from initial discovery to final approval. These CROs offer a comprehensive range of services, including clinical trial management, data research, and project management. Their critical role has become even more evident during the pandemic-induced challenges, where the need for rapid vaccine and drug development resulted in a surge of clinical trials.

The Impact of Covid-19 on Clinical Trials

At the outset of the pandemic, the clinical research landscape faced initial setbacks. However, the urgency to combat Covid-19 created an unprecedented rise in the number of clinical trials. The pressing demand for effective vaccines and treatments drove pharmaceutical companies and CROs to collaborate more than ever before. Looking ahead, the future of CROs appears promising, fueled by the rise of technologies that enable decentralized clinical trials. These modern approaches leverage digital tools and remote patient monitoring, reducing the need for physical site visits and expanding the reach of clinical research.

The Growth of the Global CRO Services Market

The significance of CROs is evident as the global CRO services market continues to expand exponentially. Projections indicate that this market, which was valued at US$76.6 billion , is expected to reach an impressive US$127.8 billion by 2028. This growth reflects the pivotal role CROs play in revolutionizing drug development and medical research.

Source: Markets&Markets

Unveiling the Best 10 Clinical Research Organizations in the Field

Join us as we embark on this insightful journey, where we shine a spotlight on the ten biggest CROs shaping the pharmaceutical landscape. –

Source: Lablcorp

Labcorp, a leading provider of comprehensive drug development solutions for various industries, achieved a significant milestone in 2015 with its acquisition of Covance for an impressive $6 billion. This strategic union brought together Covance's expertise in drug development and Labcorp's unparalleled medical testing capabilities, propelling the company to become the world's foremost healthcare diagnostics company.

Over the past decade, Labcorp has continued to expand its influence through a series of strategic acquisitions. Notable additions to their portfolio include LipoScience, Inc., Bode Technology Group, Sequenom, MNG Laboratories, and Personal Genome Diagnostics (PGDx). These acquisitions have further strengthened Labcorp's position in the market, broadening its scope and enhancing its ability to provide cutting-edge solutions.

Looking forward to 2023, Labcorp unveiled its plans to spin off its Contract Research Organization (CRO) segment, creating a separate, independent publicly traded entity known as Fortrea.

Source: IQVIA

In 2016, two industry giants, Quintiles and IMS Health, joined forces and rebranded as IQVIA, establishing the largest Contract Research Organization (CRO) globally. With a presence in over 100 countries, IQVIA brings together cutting-edge advancements in data science, technology, and human science expertise, offering clients a comprehensive end-to-end clinical and commercial service. Through a series of strategic acquisitions of smaller specialist companies, IQVIA has strengthened its position and continues to lead the way in the world of CROs.

In the year 2022, IQVIA demonstrated remarkable growth and success, generating revenues of $14.494b . This impressive growth, amounting to 3.29% on a reported basis and 7.8% at constant currency , highlighted the company's continued upward trajectory. Despite uncertain market conditions, IQVIA achieved record bookings and surpassed the goals set in their Vision 22 plan, underscoring their commitment to excellence and innovation.

Source: Parexel

Parexel continues to hold its position as one of the largest CROs globally. Specializing in Phase I to IV clinical development services, Parexel plays a vital role in expediting and ensuring the smooth progress of the drug approval process. With a comprehensive array of service offerings, the company caters to nearly every aspect of clinical trial management, supporting sponsors in conducting successful clinical studies.

In a significant development in November 2021, Parexel was acquired by EQT Private Equity and Goldman Sachs for a remarkable $8.5 billion . Despite this transition, the commitment to putting patients first remains unwavering, ensuring that Parexel maintains its patient-centric trajectory. The newly constituted board of directors brings together a wealth of experience in the life sciences industry, further strengthening Parexel's position as a leader in the field.

4. Pharmaceutical Product Development (PPD)

Source: PPD

Pharmaceutical Product Development (PPD) stands as a leading global Contract Research Organization (CRO) with an extensive workforce of over 30,000 professionals worldwide.

The acquisition of Evidera in 2016 marked a significant milestone for PPD, solidifying their position as a leader in real-world research. Leveraging Evidera's expertise in real-world evidence, PPD has enhanced its capabilities in providing life science companies with a crucial element of the clinical development process, maintaining a competitive edge in the industry. Subsequent strategic acquisitions of Synexus (now Accelerated Enrollment Solutions) and Bioclinica, both patient recruitment and clinical research site businesses, respectively, have further augmented PPD's offerings. These collective advancements have propelled PPD's core organic growth to "high teens" in the segment, as the company achieved remarkable full-year 2022 results. With over $7.00 billion in revenue and a significant contribution of over $2.00 to adjusted earnings per share, PPD remains a dominant force in the CRO landscape, upholding their mission to facilitate groundbreaking clinical research and development.

5. Syneos Health

Source: Syneos Health

Founded in 1999, Syneos Health has its headquarters in Morrisville, North Carolina. With an impressive annual revenue of $5,213 million and a workforce of 28,000 employees, Syneos Health is a leading international Contract Research Organization (CRO) that offers a wide range of services spanning all aspects of bringing new therapies and products to the market.

While Syneos Health provides clinical development services across all stages of drug development, it has particularly specialized expertise in assisting healthcare organizations during the late stages of clinical trials. Some of them include Early phase trials, Late phase trials, Decentralized clinical trial solutions, Clinical data management, Pharmaceutical trial services, Medical device diagnostics trial services, and more.

Source: ICON

Operating across 46 locations worldwide, ICON is a top-tier Contract Research Organization (CRO) that provides a comprehensive range of services, including consulting, clinical development, and commercialization services.

In a pivotal move in 2016, ICON formed strategic partnerships with Genomics England for the UK's ambitious 100,000 Genomes Project and IBM Watson for oncology research support. These collaborations expanded ICON's service offerings and strengthened their presence in the fields of genomic science and oncology research, creating new opportunities for clinical research jobs in these cutting-edge sectors.

Additionally, the year 2022 marked a significant milestone for ICON, as it achieved impressive financial results. With full-year revenues amounting to US$7.7 billion , the company witnessed substantial growth of 41.2% compared to the previous year. On a constant currency basis, the revenue surge reached an outstanding 45%, reflecting ICON's continued success in advancing clinical research and serving as a leading partner for the life sciences industry.

7. Charles River Laboratories

Source: Charles River Lab.

Since its inception in 1947, this company has grown into an exceptional industry leader, specializing in cutting-edge cell and gene therapies. Not only does it provide vital lab services to the pharmaceutical, medical device, and biotech industries, but it also stands out with its impressive global presence. With a robust network spanning over 110+ facilities scattered robust network spanning over 110+ facilities scattered across 20+ countries, the company offers unmatched accessibility and support to clients worldwide, solidifying its reputation as a trailblazer in the field.

As of the latest data available in 2023, the company boasts an impressive annual revenue of 4.092B, a 12.73% increase year-over-year , reflecting its strong position in the market and significant contributions to the life sciences industry.

Source: CTI

CTI Clinical Trial and Consulting Services has been making waves in the industry since its establishment in 1999. With a remarkable track record of driving over 150 new drug and medical device approvals, the company has firmly established itself as a leader in the field.

Boasting a vast international footprint, CTI operates offices in more than 60 locations across the globe, ensuring its presence and support in key regions such as North America, Europe, Latin America, Middle-East, Africa, and Asia-Pacific. In a strategic move in 2021, CTI further bolstered its position by announcing the acquisition of Dynakin, a European-based strategic consulting company. This acquisition aimed to fortify CTI's standing as a comprehensive and dynamic full-service clinical research organization, ready to take on the challenges of a rapidly evolving healthcare landscape.

Source: Medpace

MEDPACE is a global organization with a workforce of over 5,000 employees spread across 40 countries. In 2022, Medpace reported an impressive full-year revenue of $1.46 billion, reflecting a substantial 27.8% increase from the previous year. In an earnings call, Jesse Geiger, the President at Medpace, highlighted the company's ability to grow its workforce by 15.8% despite facing challenges in a competitive labor environment. In 2023, Medpace places significant emphasis on employee retention and ongoing recruitment as top priorities to support its future business endeavors.

10. Fisher Clinical Services

Source: Thermo Fisher

Fisher Clinical Services is a vital division of Thermo Fisher Scientific with a rich history of over two decades in supply chain management. The company's core focus centers on efficiently handling the distribution and packaging requirements for clinical trials conducted worldwide.

With an impressive annual revenue of $20 billion and a workforce of 70,000 employees, Fisher Clinical Services is dedicated to delivering high-value products that align with the rigorous standards of pharmaceutical companies, ensuring reliability, sustainability, and optimal performance. The company plays a crucial role in supporting the success of clinical trials across the globe.

In conclusion, the best Clinical Research Companies in the USA serve as indispensable partners for pharmaceutical, biotech, and medical device industries embarking on new medicine and medical device development. With the complexities of clinical trials escalating, CROs play a pivotal role in managing and leading these trials efficiently amidst rising prices, stringent regulations, and tighter deadlines.

As the pharmaceutical landscape continues to evolve, pharmaceutical companies are increasingly turning to Clinical Research Organizations for their R&D activities to maintain competitiveness, flexibility, and profitability. With their proven track record, comprehensive services, and commitment to excellence, the best Clinical Research Companies in the USA stand as crucial allies in the quest to advance medical science and improve patient outcomes. Through fruitful partnerships with CROs, the pharmaceutical, biotech, and medical device industries continue to push the boundaries of innovation and deliver life-changing products to those in need.

Healthcare Databases

• Healthcare Email List

Doctors Email List

• Nurses Email List
• Medical Executives Email List
• Physician Email List
• Dentist Email List
• Pharmacist Email List
• Healthcare SIC Code
• Healthcare NAICS Code
• Chiropractors Email List
• Veterinarian Email List
• Radiologists Email List
• Psychiatrists Email List
• Pediatrician Email List
• Cardiologists Email List
• Neurologist Email List
• Dermatologist Email List
• Oncologists Email List

Medical Services

• Hospitals Email List
• Pharmacy Email Database
• Nursing Homes Email List
• X-Ray Laboratories Mailing List
• Pharmaceutical Email List
• Assisted Living Email List
• Dental Clinics Email List
• Clinics Email List
• Physical Fitness Facilities List

HealthcareMailing

• +1 (786) 408 5757
• [email protected]

• Privacy Policy

• ICH GCP (De)
• ICH GCP (En)
• ICH GCP (Es)
• ICH GCP (Fr)
• ICH GCP (It)
• ICH GCP (Pt)
• ICH GCP (Ru)
• AUSTRALIA (NHMRC)
• JAPAN (PMDA)
• US Clinical Trials Registry
• EU Clinical Trials Registry
• Pharmaceutical Companies
• Clinical Research Labs
• Service Companies
• Clinical Research Events
• Publications
• Researchers

Top 15 Contract Research Organizations (CROs) in 2024

Post-pandemic, as drug development businesses recover and grow, CROs around the world continue to undergo profound transformation. As in previous years, 2023 will be all about mergers and acquisitions, with big players getting even bigger and smaller companies surviving thanks to niche advantages such as technological know-how or brilliant scientists among their employees.

The top 15 CROs globally would be in the following order based on 2023 revenue :

• LabCorp (Covance) , with 15.05 billion USD (2023) and 75000 employees ( Labcorp , 2024).  In February 2015, Labcorp completes its $6 billion purchase of Covance, Inc., creating the world’s leading health care diagnostics company. The combination of Covance’s drug development leadership and Labcorp’s medical testing expertise builds the market leader in central laboratory and bioanalysis services. Labcorp’s clinical trials companies, Labcorp Clinical Trials and Tandem Laboratories, align under the Covance brand.  
• IQVIA , with 14.85 billion USD  (2023) and 86000 employees (IQVIA, 2022). IQVIA, formerly Quintiles and IMS Health, Inc., is an American Fortune 500 and S&P 500 multinational company serving the combined industries of health information technology and clinical research.  IQVIA (NYSE:IQV) is a leading global provider of advanced analytics, technology solutions, and clinical research services to the life sciences industry. With approximately 86,000 employees, IQVIA conducts operations in more than 100 countries.  
• ICON (PRA) , with 7.74 billion USD (2022) and 41160 employees (ICON, 2023). From a small team of 5 people in 1990, ICON now employs over 41,100 people.  ICON has been recognised as one of the world’s leading Contract Research Organisations through a number of high-profile  industry awards .  
• Thermo Fisher Scientific (PPD) , with 7.02 billion USD (2023) and 35000 employees (Businesswire, 2023). Recognized as a global industry leader in accelerating promising medicines from early development through regulatory approval and market access, we serve pharma, biotech, medical device and government organizations with custom-tailored solutions, including full-service partnerships and functional service partnerships. As a strategic partner in clinical development and analytical services, we apply cutting edge technologies, therapeutic expertise and a firm commitment to quality to help customers deliver life-changing therapies.  
• Lonza - 6.5 billion USD,   17896 employees. Though being a contract development and manufacturing organization (CDMO), rather than a CRO, takes the 10th position with the 5.9 billion USD in sales and over 17500 employees worldwide (2023), offering “proprietary line of in silico and in vitro services for manufacturability, immunogenicity, potency assessment, humanization and protein engineering” ( https://pharma.lonza.com , 2022). Founded in 1897 in the Swiss Alps, today, Lonza operates across five continents. With approximately 17,500 full-time employees, it comprises high-performing teams and individual talent that make a meaningful difference to our own business, as well as to the communities in which we operate. The business benefits from global supply chains, but we have worked to maintain the agility to address marketplace needs on a local level. CDMOs become reliable partners for Pharma companies as their “services reduce R&D costs while improving productivity and are essential to providing safe and effective treatment to patients” ( https://pharma.lonza.com , 2022.  
• Wuxi AppTec with 5.8 billion USD revenue in 2021 and 44360 employees (Companiesmarketcap, 2022). As a global company with operations across Asia, Europe, and North America, WuXi AppTec provides a broad portfolio of R&D and manufacturing services that enable the pharmaceutical and healthcare industry around the world to advance discoveries and deliver groundbreaking treatments to patients. Through its unique business models, WuXi AppTec’s integrated, end-to-end services include chemistry drug CRDMO (Contract Research, Development and Manufacturing Organization), biology discovery, preclinical testing and clinical research services, and cell and gene therapies CTDMO (Contract Testing, Development and Manufacturing Organization), helping customers improve the productivity of advancing healthcare products through cost-effective and efficient solutions. WuXi AppTec received AA ESG rating from MSCI in 2023 and its open-access platform is enabling more than 6,000 customers from over 30 countries to improve the health of those in need – and to realize the vision that "every drug can be made and every disease can be treated."  

Syneos Health® is a leading fully integrated biopharmaceutical solutions organization built to accelerate customer success. We translate unique clinical, medical affairs and commercial insights into outcomes to address modern market realities.

We bring together a talented team of professionals, who work across more than 110 countries, with a deep understanding of patient and physician behaviors and market dynamics. Together we share insights, use the latest technologies and apply advanced business practices to speed our customers’ delivery of important therapies to patients.  

Cell and Gene Therapy CDMO Solutions has supported the development of 11 FDA approved cell and gene therapies and have conducted more than 900 studies in this field over the past year. Unsurpassed end-to-end offering results in enhanced access to scientific and regulatory expertise via multidisciplinary bench of experts to help you problem solve.   

Parexel (EQT Private Equity and Goldman Sachs Asset Management) with 3.8 billion USD in 2022 and 21000 employees (Parexel, 2023). Parexel is among the world’s largest clinical research organizations (CROs), providing the full range of Phase I to IV clinical development services to help lifesaving treatments reach patients faster. Leveraging the breadth of our clinical, regulatory, and therapeutic expertise, our team of more than 21,000 global professionals works in partnership with biopharmaceutical leaders, emerging innovators, and sites to design and deliver clinical trials with patients in mind, increasing access and participation to make clinical research a care option for anyone, anywhere.  

• Medpace Holdings, Inc. with 1.135 billion USD revenue in 2021 and 5400 employees (Medpace, 2023). Integrating core clinical trial services delivers efficient and streamlined execution and higher quality results. Through its wholly-owned subsidiaries, Medpace offers clinical pharmacology, as well as supporting laboratory services including central labs, bioanalytical lab, ECG core lab, and imaging core labs.  

Worldwide Clinical Trials – 0.6 billion USD , 3000 employees, 60 countries.

Worldwide Clinical Trials started out more than 30 years ago as a small science team with a big goal: To always provide authentic, personalized attention to our partners. And as the industry has grown, CROs have merged, and trials have grown increasingly complex, we haven’t forgotten what truly matters: People.

With more than 3,000 employees in more than 60 countries around the world, we’re still staying true to those roots. Our team is dedicated to staying accessible, flexible, and solution-focused to ensure our partners not only have the best possible outcomes – but they also know their Worldwide team is only a call away.  

Allucent (CATO SMS and Pharm-Olam) – 0.36 billion USD, 1200+ employees .

Allucent originated with CATO SMS, itself created by the merger of Cato Research and SMS-oncology in 2019. Cato Research, founded in 1988, was known for its ability to design and execute successful development strategies and guide creative new products through the regulatory process.

Previous acquisitions by CATO SMS included Array Biostatistics, a full-service biostatistical and statistical programming CRO, and Nuventra Pharma Sciences, one of the industry’s leading providers of clinical pharmacology science and services. With these acquisitions, CATO SMS expanded its services to offer biostatistical consulting, analysis, programming, and cutting-edge modeling and simulation techniques to inform clinical trial designs and predict trial outcomes.

In early 2022, CATO SMS merged with Pharm-Olam, a global clinical research organization delivering clinical trial services to organizations around the world.  

KCR – 0.15 billion USD, 700 employees  

KCR is a clinical development solutions provider creating value for biotechnology and pharmaceutical organizations.

Founded in 1997, our expert teams support clients with full-service clinical development capabilities across three main areas: Trial Execution, Consulting, and Placement. KCR operates across North America, Europe, and Australia, with main office locations in Boston, US, Berlin, Germany, and Warsaw, Poland.

Our geographical coverage across 25+ countries, cutting-edge technical capabilities and tailored offerings allow for the optimized delivery of solutions to develop life-changing therapies. KCR offers access to an estimated population of 1.1 billion people.  

Advanced Clinical – 0.1 billion USD , 1100+ employees

Today, Advanced Clinical has grown organically, with coverage across North America, Eastern Europe, Western Europe and Asia-Pacific, providing contract research organization (CRO), FSP and strategic resourcing solutions. A research services and strategic resourcing organization committed to providing a better clinical experience by delivering comprehensive Contract Research Organization (CRO), Functional Service Provider (FSP) and Strategic Resourcing services that optimize effectiveness for both patients and sponsors throughout the clinical research journey.

Using our decades of experience, we strive to improve the lives of everyone touched by clinical research and help our clients achieve better outcomes through candid conversations, foresight, resilience and innovative solutions.  

CTI Clinical Trial and Consulting Services – 0.08 billion USD, 750 employees . CTI has grown consistently and significantly, becoming a global organization with associates in more than 60 countries across the world. We have worked on more than 10,000 projects, worked on every continent except Antarctica, and have contributed to more than 150 new drug and device approvals through global regulatory agencies such as the FDA, EMA, and others. Currently, we work with approximately 250 pharmaceutical and emerging biotechnology and medical device companies.

Among recent reasons for mergers and the whole new approach to conducting clinical research, apart from pursuit of new clients, talents, expertise, products, and markets, there have been notorious coronavirus crisis and military conflicts worldwide. We faced the advent of globalization, decentralization, remote monitoring, and personalized approach to drugs R&D. But we are now looking into the era of technology in clinical research. Processes that allow remote audits and monitoring, previously considered too risky, are now risk mitigators (Bahls, Christine, 2021), at least from that point of view. Clinical trial participants enrollment, and even participation itself, constantly moves into tech dimension.

Only few among the leading CROs escaped M&As for now, but this seems to be the matter of time. Savlovschi – Wicks, Theodora (2022) estimated that “in 2021, the global CRO market is expected to reach an impressive US$88 billion by 2028”. According to IQVIA , only in biopharma sector the total transaction value grew by 70% to reach 152 billion USD by the end of 2023, featuring prominent $43Bn Pfizer-Seagen deal, and other considerable M&As for BMS-Karuna ($14Bn), Merck-Prometheus ($10.2Bn), AbbVie-Immunogen ($10.1Bn), AbbVie-Cerevel ($8.7Bn), Biogen-Reata ($7.3Bn) and Roche-Telavant ($7.1Bn).

Among the CRO businesses the following M&As took place lately:

• Charles River Labs acquires  MPI Research (2018), Citoxlab (2019), HemaCare (2020) and Cognate BioServices (2021)
• IQVIA (formerly Quintiles and IMS Health) acquired Clintec and 40% of Q2 Solutions (2021)
• ICON purchased PRA Health Services (2021)
• Thermo Fisher Scientific bought PPD (2021)
• Labcorp purchased Covance and Chiltern
• Inotiv acquired Envigo (2021)
• INC Research and inVentiv Health merged to later become Syneos Health
• Parexel become the property of EQT Private Equity and Goldman Sachs Asset Management
• CATO SMS and Pharm-Olam merged in 2022
• Triley Bidco acquired Clinigen (2022)

The article by Nataliia Vietchinkina, MS in Clinical Research Administration

University of Liverpool. 

References:

• Christine Bahls (2021) ‘The Post-Pandemic CRO Landscape’, Applied Clinical Trials, Applied Clinical Trials-09-01-2021, Volume 30, Issue 9 [online] Available from: https://www.appliedclinicaltrialsonline.com/view/the-post-pandemic-cro-landscape
• Savlovschi – Wicks, Theodora (2022) ‘Top 10 CROs to watch in 2022’ [online]. Available from: https://www.proclinical.com/blogs/2022-3/top-10-cros-to-watch-in-2022
• Labcorp (2022) Labcorp Announces 2021 Fourth Quarter and Full-Year Results, 10 February 2022 [online]. Available from” https://ir.labcorp.com/news-releases/news-release-details/labcorp-announces-2021-fourth-quarter-and-full-year-results#:~:text=Revenue%20was%20%2416.12%20billion%20%2C%20an,by%20divestitures%20of%20(0.1%25)
• IQVIA (2022) IQVIA Reports Fourth-Quarter and Full-Year 2021 Results; Raises Full-Year 2022 Profit Guidance, 15 February 2022 [online]. Available from: https://ir.iqvia.com/press-releases/press-release-details/2022/IQVIA-Reports-Fourth-Quarter-and-Full-Year-2021-Results-Raises-Full-Year-2022-Profit-Guidance/default.aspx#:~:text=Revenue%20of%20%2413%2C874%20million%20for,12.4%20percent%20at%20constant%20currency
• ICON (2022) ICON Reports Fourth Quarter and Full Year 2021 Results, 2022 [online]. Available from: https://www.iconplc.com/news-events/press-releases/icon-reports-fourth-quarter-and-full-year-2021-results/
• Businesswire (2021) ‘PPD Reports Fourth Quarter and Full Year 2020 Results’, 23 February 2021 [online]. Available from: https://www.businesswire.com/news/home/20210223006094/en/PPD-Reports-Fourth-Quarter-and-Full-Year-2020-Results
• Macrotrends (2022) ‘Syneos Health Revenue 2012-2021 | SYNH’ [online]. Available from: https://www.macrotrends.net/stocks/charts/SYNH/syneos-health/revenue
• https://companiesmarketcap.com/ (2022) ‘Revenue for Charles River Laboratories (CRL)’ [online]. Available from: https://companiesmarketcap.com/charles-river-laboratories/revenue/
• Vinluan, Frank (2021) ‘CRO Parexel changes private equity hands again, this time for $8.5B’ [online]. Available from: https://medcitynews.com/2021/07/cro-parexel-changes-private-equity-hands-again-this-time-for-8-5b/
• Medpace (2021) ‘Medpace Holdings, Inc. Reports Third Quarter 2021 Results’ [online]. Available from: https://investor.medpace.com/news-releases/news-release-details/medpace-holdings-inc-reports-third-quarter-2021-results#:~:text=The%20Company%20forecasts%202021%20revenue,%24176.0%20million%20to%20%24180.0%20million%20 .
• Companiesmarketcap (2022) ‘Revenue for WuXi AppTec (2359.HK) Revenue in 2021 (TTM)’ [online]. Available from: https://companiesmarketcap.com/wuxi-apptec/revenue/
• https://pharma.lonza.com (2022) ‘Design, assess and optimize for clinical success’ [online]. Available from: https://pharma.lonza.com/offerings/early-development-services .

Clinical Research News

Upcoming clinical trials.

• Sanofi Pasteur, a Sanofi Company Not yet recruiting Study to Evaluate the Safety and Immune Response of an Investigational Vaccine for the Prevention of RSV (Respiratory Syncytial Virus) and (hMPV) Human Metapneumovirus Infection in Participants Aged 60 to 75 Years RSV Infection | hMPV
• Peking University First Hospital Peking University Third Hospital Recruiting SABR Combined With Targeted Therapy and Anti-PD-1 for Recurrent or Metastatic Renal Cancer (COSTAR) Recurrent Renal Cell Cancer | Radiation Therapy | Metastatic Renal Cancer China
• Sun Yat-sen University Recruiting Sintilimab With P-GEMOX Versus the P-GEMOX in the Teatment of Advanced-stage Extranodal Natural Killer/T Cell Lymphoma (SPIRIT-02) Natural Killer/T-Cell Lymphoma, Nasal and Nasal-Type China
• University of Michigan Not yet recruiting College Student Stress: Transitions Over Time Depressive Symptoms
• Beijing Hospital Not yet recruiting Prediction Model of Treatment Efficacy for Age-related Macular Degeneration Based on Multi-source Imaging Modalities Age-related Macular Degeneration (ARMD)
• University of Kansas Medical Center Recruiting Ultrasound Guided Radiofrequency Ablation of the Occipital Nerve Nerve Pain
• Akdeniz University Recruiting Effect of Motivational Interviewing on Sleep Hygiene, Sleep Quality and Quality of Life Sleep Hygiene Turkey
• Emory University National Cancer Institute (NCI); National Institutes of Health (NIH) Not yet recruiting A Smoke-Free Home Intervention in Tribal Communities Tobacco-Related Carcinoma United States
• Nigde Omer Halisdemir University Recruiting Evaluation of the Relationship Between Breastfeeding Attitudes and Nutrition Knowledge Levels Breastfeeding
• Ain Shams University Not yet recruiting Conventional Spinal Anaesthesia Versus Fractional Spinal Anaesthesia on Hemodynamics Hip Fractures
• University of Maryland, Baltimore Not yet recruiting Hub-Based Engagement Navigator Service to Reduce CSC Disengagement Disengagement
• Xiangya Hospital of Central South University Recruiting Effect of Multimodal Monitoring Cluster Management on Patients with Severe Traumatic Brain Injury Multimodal Monitoring

Clinical Research Jobs

Sponsors and Collaborators

• Assiut University
• GlaxoSmithKline
• National Cancer Institute (NCI)
• Cairo University
• AstraZeneca
• Assistance Publique - Hôpitaux de Paris
• Mayo Clinic
• M.D. Anderson Cancer Center
• Novartis Pharmaceuticals
• National Institute of Allergy and Infectious Diseases (NIAID)
• Massachusetts General Hospital
• National Taiwan University Hospital
• Boehringer Ingelheim
• Hoffmann-La Roche
• Merck Sharp & Dohme LLC
• Stanford University
• University of California, San Francisco
• Eli Lilly and Company
• Duke University
• View Full List

Medical Conditions

• Breast Cancer
• Hypertension
• Prostate Cancer
• HIV Infections
• Coronary Artery Disease
• Heart Failure
• Diabetes Mellitus, Type 2
• Colorectal Cancer
• Lung Cancer
• Schizophrenia
• Cardiovascular Diseases
• Atrial Fibrillation

Drug Interventions

• Cyclophosphamide
• Carboplatin
• Dexamethasone
• Gemcitabine
• Capecitabine
• Bevacizumab
• Pembrolizumab
• Methotrexate
• Oxaliplatin
• Dexmedetomidine
• Fludarabine

Learn how our solutions can help you advance your oncology drug development. Meet with our team at the European Society of Medical Oncology (ESMO) Congress at booth 522 in Barcelona, Spain, on Sept. 13-17.

We’ve been named a leader in digital solutions and services by ISG for the fourth straight year, affirming our commitment to our customers and patients around the world.

Our new GMP lab building in Middleton, Wisconsin, will enhance services in new and emerging therapeutic areas and add 350 new jobs to the region.

It’s time for a partner who drives you forward. Let’s devise strategies that position you to meet key milestones, faster.

Drive your drug development program forward. Partner with a leading provider of global clinical research solutions .

Unrivaled therapeutic expertise honed over decades

Deep expertise that covers more than 20 therapeutic areas, from established drug markets to cutting-edge R&D, to perform studies with exceptional quality.

Solutions tailored to accelerate your development

Dependable project management and delivery, underpinned by a global network, integrated data ecosystem and people-first approach.

Comprehensive laboratory services that transform drug development

Laboratory services built on innovation and award-winning technologies to enhance clinical trial performance and regulatory success.

Bring your life-saving therapies to the world

Transformative strategies that empower you to achieve key milestones faster. Because every moment counts in clinical research.

PPD FSP Solutions

The biotech mindset, optimized study planning, insights hub.

Learn more about ACRO’s advocacy efforts in the United States and Europe

Listen to the new season of ACRO’s Good Clinical Podcast!

Artificial Intelligence & Machine Learning

ACRO’s AI/ML Committee brings together member company subject matter experts engaged in the development and use of AI/ML tools in the design, conduct, oversight, and analysis of clinical trials.

Diversity & Inclusion in Clinical Trials

ACRO’s Diversity and Inclusion in Clinical Trials Committee was formed in 2020 as a part of ACRO’s ongoing efforts to work towards advancing diversity, equity, and inclusion in the clinical research ecosystem.

Risk-Based Quality Management

Risk-based monitoring is an adaptive approach that directs monitoring focus and activities to the evolving areas of greatest need which have the most potential to impact patient safety and data quality.

ACRO MEMBERS

US Advocacy

ACRO works with US legislators and regulators to ensure a positive regulatory environment that supports high-quality, safe and ethical clinical research.

European Advocacy

ACRO engages with regulators and policymakers in the EU and UK to ensure a positive regulatory environment that supports high-quality, safe and ethical clinical research.

ACRO’s Mission

ACRO advocates as the collective voice of innovative clinical research and technology organizations to regulators and policymakers, educating stakeholders and advocating for policies that foster efficient, effective and safe conduct of clinical research.

Explore end-to-end solutions throughout development — from portfolio optimization and regulatory strategy, to Phase I-IV clinical trials, market access planning, and more.

• Portfolio management and asset valuation
• Early development and innovation
• Integrated clinical development
• Approval and access
• Value substantiation lifecycle management

HOW WE DO IT

• Delivery models
• Operational excellence
• Medical affairs
• Building patient insights into assets, profile and claims
• Portfolio optimization
• Asset valuation and indication prioritization
• Early evidence review
• Model-based drug development
• Integrated development strategy and planning
• Phase I Clinical Trials
• Proof of Concept Studies: Phase IB-IIA
• Patient Engagement Strategy and Enrollment Solutions
• Patient Inclusion
• Site Alliance Network and KOL Engagement
• Protocol Optimization
• Regulatory Strategy
• Market Access Strategy and Delivery
• Biomarker and Genomic Medicine Strategy
• Clinical Trial Supply & Logistics
• Medical Communications
• Phase IIB-IV Clinical Trials
• Operationalize post-trial access with a proven platform approach
• Protocol-Driven, Customized Site Solution Strategy
• Regulatory Strategy, Submissions, Compliance, and Outsourcing
• Clinical Development Technology Optimization
• Real World Evidence
• Global Regulatory Submissions and Outsourcing
• Compliance and Risk Management
• Real-World Evidence, Market Access Strategy and Planning
• Regulatory Compliance, Drug Safety and Pharmacovigilance
• Lifecycle Optimization
• Gain an advantage through FSP
• Leveraging AI and digital in clinical development

Parexel Biotech provides the end-to-end capabilities you’ll need to succeed. We're fast, flexible, and dedicated to impacting patient lives.

Utilize our expertise across therapeutic areas, combining innovative trial designs, leading clinical and regulatory expertise, global reach, and a passion for changing patient lives.

• Neuroscience
• General medicine
• Infectious disease & vaccines
• Inflammation & immunology

Cross-Therapeutic Expertise

• Cell & gene therapies
• Rare diseases

Our experts help you stay at the forefront of the industry - and ahead of change.

New Medicines, Novel Insights

• Advancing precision oncology
• Advancing rare disease drug development
• Accelerating development of cell and gene therapies
• Achieving patient-guided drug development

Discussions on Diversity

• Chapter 1 Bridging the Gap
• Chapter 2 Beyond the Binary

The Regulatory Navigator

• Gene therapy: are high costs and manufacturing complexities impeding progress?
• New FDA draft guidance: Implications for simplifying interchangeability for biosimilars in the US
• Key implications for nonclinical development: FDA guidance on human gene therapy products incorporating human genome editing

Latest Report

New Medicines, Novel Insights: Advancing precision oncology

Thinking about joining a clinical trial? Learn the drug development process, what it’s like to participate, how to find a trial, and answers to frequently asked questions.

INTERESTED IN PARTICIPATING?

• Healthy Volunteers
• Patient Volunteers
• Patient Advocacy Groups

HEAR FROM REAL PATIENTS

• Patient Stories

TRIAL SITES

Want to collaborate with us to offer clinical trials at your site? We would welcome the opportunity to discuss.

We are one of the largest CROs in the world, speeding life-changing medicine to market by engaging patients With Heart ™. Learn about who we are, what we do, and what we believe.

• Leadership team
• Global reach
• Our DE&I strategy
• Compliance, tax & privacy
• Meet us at an event
• Board of Directors
• Our ESG strategy
• Compliance & Ethics
• Tax Strategy
• Privacy Policy
• Cookies and other web tracking
• Supplier Data Privacy Requirements
• Terms of Use
• French Gender Pay Data
• UK Gender Pay Data
• UK Modern Slavery Act Statement
• Data Privacy Framework
• Supplier Diversity Policy

What can we help you find today?

The perspectives and opinions expressed in this material represent those of the patient advocate only and should not be considered a solicitation, promotion or advertisement for any services of Parexel, or any drugs or therapies, including those under development. Participating in clinical trials for investigational medicines offers patients potential benefits, such as access to cutting-edge treatments and expert medical care, while contributing to medical research. However, risks may include side effects, unpredictable outcomes, and time commitment. Careful assessment of these factors helps patients make informed decisions. The content of this material, including graphics, images and text, is provided for informational purposes only and does not constitute medical advice, diagnosis or treatment. Please consult your healthcare professional for medical advice. The patient advocate has provided their consent for the use and distribution of this content.

Patient Story

Rare Diseases

• Inflammation & Immunology

Cell & Gene Therapy

While running a triathlon, andrea stumbled and realized something was wrong..

Her condition worsened. Within months, she was forced to walk with a cane.

Then, finally, came the diagnosis.

She thought it was just an injury. Her hamstrings were tight, and her body felt stiff and slow.

She had als, a condition affecting more than 200,000 people around the world., her life expectancy was shortened to just two to five years — but she was determined to make the most of it., andrea continued to join triathlons, even as she underwent treatment in a clinical trial, inspiring many and raising $1,000,000 for als research., today, alive beyond her original prognosis, she serves on our patient advisory council, using her experiences to help improve our neuroscience trials., lives can change when you design neuroscience trials with speed and precision..

• Utilize the right experts, with the right specialization
• Find the patients you need and earn their trust
• Satisfy global regulations to get your treatment to patients safely and quickly
• Design studies and endpoints with market access in mind

What we do, we do

Our Experts

Our neuroscience specialists collaborate to get your treatment to patients faster.

MORE EXPERTS

Antal János, M.D., M.B.A.

Vice President, Glob...

Karla Kanis, M.D.

Mohit Verma, M.D.

Global TA Section He...

Andreas Lysandropoulos, M.D., Ph.D.

Senior Vice President, Global Neuroscience Therapeutic Area Head

With 15+ years of experience as a clinical neurologist, principal investigator, and medical leader, Andreas works with you to create an effective development strategy. Once the plan is in place, he and his team lead all aspects of execution — ensuring your assets are approved quickly and efficiently.

"For me, ‘With Heart’ means with passion and empathy. It is my mission to gather people around a common cause and inspire everybody to reflect on and be passionate about what we do together because it matters to patients who rely on us all for a better life."

Our diverse neuroscience experiences ensure you get the expertise you need across all indications of neurology and psychiatry.

Innovative trial designs allow us to optimize your trials for maximum impact.

Neuroscience sites around the world allow us to accelerate study startups.

• North America
• South America
• Middle East & Africa

Advanced modeling and simulation allow us to predict drug effects ahead of time, saving time, money, and resources.

And our patient-first approach results in deeper, more relevant insights for trial design and execution.

BENEFITS MAY INCLUDE

What can we do to help you change patient lives?

See neuroscience capabilities Visit all therapeutic areas Explore neuroscience careers

Discover other patient stories

Sara's only symptom was fatigue. But after some routine tests, she was diagnosed with breast cancer.

When Austin was 3 years old, his parents realized something was wrong. Multiple falls, concussions, and a broken arm led to a diagnosis.

Tina had lost her father to Crohn's disease. Now she faced her own diagnosis — and it derailed her life.

One night, while watching TV with her husband, Robyn felt a lump in her neck. As a doctor, she knew the risk.

We focus on patients, because they inspire us to deliver better trials, faster than ever . So we can make a difference for more patients everywhere.

Who we are,, parexel is proudly among the world’s largest clinical research organizations.

A dedicated CRO providing the full range of Phase I to IV clinical development services  and leveraging the breadth of our clinical, regulatory and therapeutic expertise , our team of more than 21,000 global professionals works in partnership with biopharmaceutical leaders and sites to design and deliver clinical trials with patients in mind , to make clinical research a care option for anyone, anywhere.

10 Best Clinical Research Organizations In The USA

With the growing population, diseases affecting mankind are also increasing. The old medications are being obsolete for certain diseases like bacterial infections, and new effective medicines are urgently needed. The clinical research institutions facilitate drug manufacture by running preclinical and clinical tests on the drugs. In addition, they also study safety, efficacy, and effectiveness of medical devices, diagnostic products, and treatment regimens intended for human health. The healthcare industry is booming with a lot of clinical research institutions in the US and all around the world.

Table of Contents

Top 10 American CROs

The United States of America has some of the top clinical research organizations in the world. Amongst them, here is the list of the 10 Best Clinical Research Organizations In The USA.

Annual Revenue: $9.6B Headquarters: Princeton, New Jersey Number of Employees: 50,000+ Total Funding: $0 Status: Public, Subsidiary of LabCorp Founded: 1996

In 2014, LabCorp acquired Covance for $6.1B. Covance, a global contract research organization under LabCorp, is the world’s leading healthcare diagnostics company, providing comprehensive clinical laboratory services and end-to-end solutions for drug and diagnostics development and commercialization. With its mission to bring new and innovative medicines to patients sooner, it has worked on more than 50 drugs available in the market today. It provides drug development services across all phases of development and multiple therapeutic areas.

Annual Revenue: $9.74B Headquarters: Durham, North Carolina Number of Employees: 55,000 Operating Income: $1.33B Status: Public, Independent Company Founded: 1982

Working to enhance healthcare by integrating health information technologies and clinical research, IQVIA explores a new path to better health outcomes via Human Data Science. It integrates the study of human science with breakthroughs in data science and technology to advance our understanding of human health, and help everyone make better, more insightful decisions.

3. Syneos Health

4. parexel international.

Annual Revenue: $2.4B Headquarters: Waltham, Massachusetts Number of Employees: 18,660 Total Funding: $0 Status: Public, Subsidiary of Pamplona Capital Management LLP Founded: 1982

5. PRA Health Sciences

Annual Revenue: $2.7B Headquarters: Raleigh, North Carolina Number of Employees: 16,400 Total Funding: $305.6M Status: Public, Subsidiary of Kohlberg Kravis Roberts & Co. L. P Founded: 1976

PRA participated in the pivotal or supportive trials and/or key NDA support services that led to the approval of 85 important products currently on the market. Its aim is to improve the drug development process for getting better medicines to market sooner.

6. Pharmaceutical Product Development

Annual Revenue: $1.9B Headquarters: Wilmington, North Carolina Number of Employees: 18,583 Total Funding: $0 Status: Private, Independent Company Founded: 1985

PPD applies innovative technologies, therapeutic expertise, and a firm commitment to provide comprehensive, integrated drug development, laboratory, and lifecycle management services. Its clients and partners include pharmaceutical, biotechnology, medical device, academic, and government organizations. It helps to bend the cost and time curve of drug development and optimize value in delivering life-changing therapies to improve health.

7. Charles River   Laboratories

Annual Revenue: $2.27B Headquarters: Wilmington, Massachusetts Number of Employees: 14,700 Total Funding: $224M Status: Public, Independent Company Founded: 1947

Icon helps its clients to accelerate the development of drugs and devices that save lives and improve quality of life. It offers a full range of consulting, development, and commercialization services from a global network of offices in 37 countries.

9. WuXi AppTec

10. medpace holdings.

Annual Revenue: $704.6M Headquarters: Cincinnati, Ohio Number of Employees: 2,900 Total Funding: $161M Status: Public, Subsidiary of Cinven Limited Founded: 1992

Medpace provides services for Phase I-IV of drug and medical device development services, including regulatory services and central laboratory services. It combines scientific guidance, efficient clinical trial management, global regulatory leadership, and innovative technologies to deliver high-quality results.

Related Posts

Top 10 medical device companies in the world, top 10 jobs you can get in the biotechnology sector, top 10 biotechnology universities in the world.

Making explorers dreams happen

We create value for the life science industry by rapidly identifying and delivering clinical development solutions.

Search our services by patient access or therapeutic areas

Alice Catherine Evans (1881 – 1975), American Microbiologist

News & Articles

We stay proactive and think big. Stay informed about our latest research news.

Clinical Trial Careers

From pharmacovigilance to clinical research specialists and everything in between, you’ll make an impact on the livelihood and wellbeing of people.

Investigative site network

We value your contribution to improving healthcare. Join our research organization in bringing lifechanging therapies directly to the ones who matter most.

Discover the real world of clinical trials.

From the patient perspective.

“For us, innovation is a development strategy that allows us to differentiate our FSP offerings by including the most advanced technology in a sensible and responsible manner.”

“Modern R&D is certainly continuing to push the bar for the application of innovative therapies. (…) Consulting options are readily available and provide access to like-minded teams that can facilitate commercialization at the right pace and an acceptable cost.”

“My ultimate hope working as a CTO for a growing and successful CRO is that we see a new DCT solution that builds from a core platform and then leverages this core in the development of component parts in order to achieve a true clinical trial lifecycle… for all stakeholders.”

• Applied Clinical Trials

This website collects only necessary cookies and analytical cookies; no personal identifiable information will be collected.

By clicking “Accept All Cookies,” you will allow us to gain valuable insights to enhance your user experience and our website.

A Better Clinical Experience . What Others Only Promise, Advanced Clinical Delivers

Welcome to advanced clinical.

A research services and strategic resourcing organization committed to providing a better clinical experience by delivering comprehensive Contract Research Organization (CRO), Functional Service Provider (FSP) and Strategic Resourcing services that optimize effectiveness for both patients and sponsors throughout the clinical research journey.

Using our decades of experience, we strive to improve the lives of everyone touched by clinical research and help our clients achieve better outcomes through candid conversations, foresight, resilience and innovative solutions.

Extensive experience across Phases I-IV in all major therapeutic areas

One driven team with a 92% employee retention rate

A customized and flexible approach with a 77% repeat business rate

High satisfaction ratings, with sites consistently rating us an average of 4.7 on a 5-point scale for over 27 consecutive calendar quarters

Access to industry-leading experts and technology

Award-winning leaders and culture, with nine years as a Chicago Tribune Top Workplace

Our Latest Updates

• Knowledge Hub

MSP & VMS Strategic Staffing Partner for a Better Clinical Experience

Clinical trial trends and the rise of site networks, trends in clinical trial innovation for 2024 and beyond, advanced clinical announces opening of new office in india.

July 30, 2024

ADVANCED CLINICAL NAMED 2024 BEST OF STAFFING® CLIENT AND TALENT DIAMOND AWARD WINNER

February 6, 2024

ADVANCED CLINICAL NAMED ONE OF CRAIN’S BEST PLACES TO WORK IN CHICAGO 2023

September 14, 2023

Clinical Trials in Rare Diseases

September 10-11, 2024 San Francisco, CA

ESMO Congress

September 13-17, 2024 Barcelona, Spain

September 17-18, 2024 Philadelphia, PA

Discover Advanced Clinical's Solutions.

Velocity is the world's leading integrated site organization.

Sponsors and cros trust velocity to deliver high-quality clinical trial data and patient care with unprecedented efficiency., simplify everything from site selection to study close-out.

Velocity unifies operational processes to provide world-class sites, reliable enrollment, and predictably high performance for your trials.

The right sites. The right investigators. The right partner for you.

Strategically located to give you access to diverse specialty populations, Velocity's sites are supported by next-gen technologies and patient engagement capabilities. Welcome to recruitment and retention reimagined.

Scale for a purpose: Supporting research programs worldwide

From the leading pharma companies, to the most pioneering biotech startups, Velocity supports those who are exploring new frontiers in human health.

Whether you’re ready to conduct a single-site study or a complex, high-volume clinical trial, contact Velocity.

Drs. Essink and Overcash Author Article Featured in Nature Communications for Moderna COVE Study

Brandon Essink, MD, CPI, and J. Scott Overcash, MD, were authors of a recent Nature Communications article, “Long-term safety and effectiveness of mRNA-1273 vaccine in adults: COVE trial open-label and … Read more

VISIOIN Reaches $2 Million in Patient Stipends Paid Globally

Since launching in-app stipend payments, Velocity has paid more than $2 million to patients globally through VISION. The mobile app has also contributed to more than 2,500 patient randomizations, empowering … Read more

Kris Kowdley, MD, Supported Research Leading to Accelerated FDA Approval of Gilead’s Livdelzi® for Primary Biliary Cholangitis

Another milestone for patients with primary biliary cholangitis (PBC) — Gilead’s Livdelzi® (seladelpar) has received accelerated FDA approval as a second-line treatment for PBC. Kris Kowdley, MD, AGAF, FAASLD, FACP, … Read more

An interview with Dr. Robert Cupelo on Alzheimer’s Treatment and the Legacy of Lecanemab

It’s been just over a year since the monoclonal antibody Lecanemab received traditional approval from the FDA as a treatment for Alzheimer’s disease. This marked a turning point in the … Read more

Quality. Continuity. Velocity.

To provide the best experiences, we use technologies like cookies to store and/or access device information. Consenting to these technologies will allow us to process data such as browsing behavior or unique IDs on this site. Not consenting or withdrawing consent, may adversely affect certain features and functions. Cookie Policy (US)   Cookie Policy (EU)   Cookie Policy (UK)

WorldwideEdge™

You are always looking to make improvements in science, and we are too..

Recognized for Excellence.

Find out why we were the highest-rated ph i service provider for overall user preference and the highest-rated ph ii/iii cro for overall performance., discover why your cro search is over.

You and your work matter here.

Accessible partners. Shared commitment. Personalized for you. 

Discover why it’s a world of difference at Worldwide.

Clinical research isn’t a straight path. let’s navigate it together..

At Worldwide, we believe a personalized approach is the only way to unlock the power of everyone working on a study – from operational and therapeutic experts to site partners and scientists. That means you’ll always have direct access to our experts. You’ll be able to tap into more than 30 years of therapeutic experience on a global scale. And your mission is our mission – we are dedicated to working with you to meet your goals.

Addressing the Top Concerns & Unmet Needs in Oncology Clinical Research

Worldwideedge: driving innovation in bioanalytical lab run success rates.

Press Release

Worldwide Clinical Trials Recognized with Coveted 2024 CRO Leadership Awards Based on Customer Feedback for 11th Consecutive Year

Want a cro partner who gives you their full attention, you’re in the right place..

Therapeutic Experts

Countries, All Regions

Michael Murphy, MD, PhD Chief Medical and Scientific Officer

Your extended team…always within reach.

We were founded on an unwavering commitment to therapeutic excellence and personalized attention. And today, that’s more important than ever. That means you have access to our senior-level experts who will work directly with you. It means we listen to you, understand your study’s needs, and actively seek customized solutions that are tailored to your specific project – even if we need to pivot and adapt along the way.

Every study is different. Every path forward is different. And we will partner with you every step of the way.

Aman Khera, MBA, FTOPRA, FRAPS Vice President, Regulatory Science, Strategy and Innovation

Flexible? Check. Responsive and nimble? Absolutely.

We understand that no clinical trial looks the same. Your trials deserve solutions backed by decades of therapeutically relevant and adaptable expertise. That’s exactly what we bring to the table.

When you partner with Worldwide, we’ll stay by your side through the entire lifecycle of product development with nimble, solutions that are never “just off the shelf” but customized for you and your specific needs.

Let’s work together to bring clarity to complex drug development.

Schedule a consultation.

Want to see what’s possible? Connect with us!

Request a Proposal

Ready to work with a CRO partner who gives you our full attention?

Meet Us at an Event

Where in the world is Worldwide? If you’ll be at an upcoming event, let’s connect! Here’s where we’ll be:

Paris MASH Meeting

2024 ESMO Congress

Customer Appreciation Event

OCT Southern California

Send Us a Message

A member of the team is online now to help address your needs.

Explore Open Careers

Cookies on the worldwide clinical trials website.

We use cookies to improve your browsing experience and help us improve our websites. We have carefully selected third parties that use cookies to achieve purposes illustrated in the cookie policy. For more information. Read more about online privacy statement . By closing this banner or continuing to browse our website, you agree to our use of such cookies.

Novum Pharmaceutical Research Services

Global footprint, vast therapeutic expertise and seamless execution, latest news.

Accelerate your Phase-1 Clinical Trials With Novum

Message from the Managing Director’s Desk

At Novum Pharmaceutical Research Services, our dedicated focus revolves around providing comprehensive end-to-end clinical research services to the global innovator, biotech, and generic pharmaceutical industries. We consistently set new standards in the clinical research sector, achieving milestones through both organic growth and strategic acquisitions.

In 2019, Lambda Therapeutic Research strategically expanded its North American presence by acquiring Novum Pharmaceutical Research Services, a distinguished 50-year-old CRO. This strategic move, following the integration of Biovail’s R&D facilities in Canada in 2010, marked Lambda’s second significant acquisition in North America. Operating under the unified brand of Novum Pharmaceutical Research Services in North America, Lambda reinforces its position as a key player in the global CRO market.

Leveraging the trusted Novum brand, we are committed to delivering a seamless and enhanced suite of services across our North American operations. Over the past years, we have upheld an impeccable regulatory track record, successfully navigating various international inspections across our global units. We have also bolstered our clinical trial management capabilities by investing in top-tier scientific talent and expanding our global network of clinical sites. Our dedication to exceeding client expectations is unwavering, as we continue to offer a comprehensive portfolio of early and late-phase services.

With a focus on integrity, innovation, and client satisfaction, we are confident that our efforts will continue to meet and surpass client expectations, always

Bindi Chudgar Managing Director

​Turnkey Clinical Trial Management solution for YOUR drug development programs

Guided by a senior management team with expertise in science, operations, quality assurance, medical affairs and project management, Novum offers the highest levels of integrity and reliability.

Phase I Early Clinical Development

Phase II-IV Clinical Trial Management

Scientific Affairs

Bioanalytical

Nearly fifty years of high-quality research outcomes.

Novum is a full-service CRO with an impeccable performance record and numerous FDA approvals in new drug, 505(b)(2) and ANDA submissions. We manage complex studies across numerous therapeutic areas and dosage forms, spanning early phase to late phase trials. With the full integration of our bioanalytical unit in Toronto, Canada in 2020, Novum is poised to continue its longstanding tradition of serving clients with safety, quality, and scientific leadership.

There are plenty of ways to get in touch. Just select the one that is best for you.

Novum prides itself on its talented and dedicated team of employees. The Novum team is passionate about customer satisfaction, safety and study integrity. All Novum clinical staff members receive extensive training designed to continually hone and increase the skills of each employee.

Want to participate in a study?

Last year we paid over $6.6 million to participants of our research studies.

This website stores cookies on your computer. These cookies are used to collect information about how you interact with our website and allow us to remember you. We use this information in order to improve and customize your browsing experience and for analytics and metrics about our visitors both on this website and other media. To find out more about the cookies we use, see our Privacy Policy.

If you decline, your information won’t be tracked when you visit this website. A single cookie will be used in your browser to remember your preference not to be tracked.

Why Catalyst Clinical Research?

You need someone to listen to your needs. You need a catalyst for your drug development needs.

Catalyst provides highly customizable clinical trial and drug development solutions to the global biotechnology and biopharmaceutical industries through our Catalyst Oncology and Catalyst Flex. Through these two solutions, Catalyst offers a full-service oncology CRO and multi-therapeutic functional service provider services.

With Catalyst, you can always count on us. We are a catalyst.

Get the latest news and press releases from Catalyst Clinical Research

• Privacy Overview
• Strictly Necessary Cookies
• 3rd Party Cookies
• Additional Cookies

This website uses cookies so that we can provide you with the best user experience possible. Cookie information is stored in your browser and performs functions such as recognising you when you return to our website and helping our team to understand which sections of the website you find most interesting and useful.

Strictly Necessary Cookie should be enabled at all times so that we can save your preferences for cookie settings.

If you disable this cookie, we will not be able to save your preferences. This means that every time you visit this website you will need to enable or disable cookies again.

This website uses Google Analytics to collect anonymous information such as the number of visitors to the site, and the most popular pages.

Keeping this cookie enabled helps us to improve our website.

Please enable Strictly Necessary Cookies first so that we can save your preferences!

This website uses the following additional cookies:

(List the cookies that you are using on the website here.)

The Science-First CRO. ™

The scientific full service cro and consultancy integrating strategic planning, regulatory strategy, and clinical trial execution to rapidly advance your complex or novel therapies..

READ THE PRESS RELEASE

Specialty Expertise

Our team of scientific experts is easy to work with, even for the rarest, most complex, and never done before novel therapies..

Driving Success

Advancing Novel Therapies to Success with Veristat READ SPONSOR SUCCESS STORIES 

Phase I/II Trial After NH Trial

Rare Disease Gene Therapy Trial

Tackling problems big or small we can help.

What Are Your Challenges?

Be Part of the Team That Cares

At Veristat, we contribute and add value to our company’s mission - improving and saving lives. Whether you’re a scientific expert or an operations guru, explore the chance to become part of our fast-paced, agile team. 

Top Clinical Research Organizations (CRO) in the United States

Patricio ledesma.

Contract Research Organization

6 January, 2020

Contact us at [email protected] if you need CRO services in the United States.

Which are the top clinical research organizations (CRO) in the United States?

The top clinical research organizations (CRO) in the United States are Covance (LabCorp), IQVIA, Syneos Health, PPD, PRA Health Sciences, and Parexel.

Covance (LabCorp)

Covance (CEO Paul Kirchgraber) is a CRO offering preclinical, clinical, and commercialization services for the pharma and biotech industries. Founded in 1996 and with headquarters in Princeton, New Jersey, Covance is a subsidiary of LabCorp and employs more than 50,000 people in over 60 nations. LabCorp’s revenue in 2018 was $11.3 billion.

IQVIA (CEO Ari Bousbib), formerly known as Quintiles, is a multinational CRO providing biopharmaceutical development, laboratory, analytical, and consulting services for phase I-IV clinical trials. Founded in 1982, and with headquarters in Durham, North Carolina, IQVIA has more than 58,000 employees in more than 100 countries. IQVIA’s revenue in 2018 was $10.4 billion.

Syneos Health

Syneos Health (CEO Alistair Macdonald) is a global CRO created through the merger of INC Research and inVentiv Health. Founded in 1984 and based in Morrisville, North Carolina, Syneos Health provides integrated biopharmaceutical solutions bringing together nearly 24,000 employees in more than 110 countries. Syneos Health’s revenue in 2018 was $4.39 billion.

PPD (CEO David Simmons) is a leading global CRO founded in 1985, providing comprehensive drug development, laboratory, and lifecycle management services. PPD’s central offices are located in Wilmington, North Carolina, and has around 23,000 employees around the world. PPD’s annual revenue in 2018 was $2.8 billion.

PRA Health Sciences

PRA Health Sciences (CEO Colin Shannon) is a multinational CRO serving the biopharmaceutical industry. With headquarters in Raleigh, North Carolina, the company was founded in 1982 and by the end of 2019 employed 15,800 people approximately. PRA Health Sciences’ annual revenue in 2018 was $2.8 billion.

Parexel (CEO Jamie Macdonald) is a global CRO offering biopharmaceutical and clinical trial management services for the clinical research sector. Parexel, founded in 1982, has central offices in Waltham, Massachusetts, and employs around 20,000 professionals operating in more than 51 countries. Parexel’s revenue in 2018 was $2.4 billion.

Request for Information

Privacy Policy

Patricio Ledesma ( B.Eng Concordia University, Montreal, Canada and Master’s Degree in Clinical Trials, University of Seville, Spain) is the Head of Clinical Operations and Founder at Sofpromed CRO. Patricio is a professional consultant providing comprehensive, one-stop expert advice and guidance to biotechnology and pharmaceutical companies worldwide in the field of clinical trials and drug development. He is personally and enthusiastically devoted to helping biotech Chief Executive, Operations, Scientific, Medical, and Regulatory Officers in the planning and execution of phase I-IV clinical trials across North America, Europe, Asia-Pacific, Latin America, and Middle East regions. You can contact Patricio at: +34 607 939 266   [email protected]  

To our articles and updates

• Follow Follow

You may also be interested…

Why Are Clinical Trials so Expensive and How Can Biotech Companies Reduce the Costs?

Clinical Trial Costs

Please contact us at [email protected] if you are looking for a cost-effective CRO Clinical trials are expensive to run due to the numerous complex and resource-intensive processes involved. In this article we explain why clinical trials are so costly, the main costs...

Why Small Biotech Startups Should Consider Small CROs Rather than Large Multinational CROs?

Please contact us at [email protected] if you need more information about Sofpromed’s CRO servicesIn this article you will learn about:[dsm_icon_list list_space_between="7px" _builder_version="4.27.0" _module_preset="default" text_font_size="16px"...

Low-Cost Rater Training for Small Biotechs Conducting CNS Clinical Trials

Clinical Data Management

Please contact us at [email protected] if you are looking for low-cost rater training services Conducting successful central nervous system (CNS) clinical trials is a complex and challenging endeavor, fraught with numerous obstacles that can jeopardize the integrity...

What Small Biotechs Need: Low-Cost CRO for Affordable Clinical Trials

Please contact us at [email protected] if you need a low-cost CRO to conduct an affordable clinical trial Clinical trials are the backbone of the pharmaceutical and biotech industries, playing a pivotal role in the development and approval of new drugs and...

Cheaper Clinical Trials for Small Biotech Startups

Please contact us at [email protected] if you need a cost-efficient CRO to run a cheaper clinical trial The biotech industry is on the cusp of a remarkable transformation, with small startups poised to revolutionize medical care through innovative therapies and...

What Is the Actual Cost of a Clinical Trial?

Check the Clinical Trial Cost Calculator here and calculate your trial budget in seconds! Please contact us and we will send you a ballpark clinical trial quotation within 48 hours. Click here if you want to download a full clinical trial quote in PDF Biotechnology...

Importance of Clinical Data Management in Clinical Trials

If you need clinical data management services for clinical trials, contact us at [email protected] Clinical data management is a fundamental element for the success of a clinical trial.In this article you will learn about:[dsm_icon_list list_space_between="7px"...

Pros of FSP Statistical Programming in Clinical Trials

FSP & Staff Recruitment

If you need FSP statistical programming services for clinical trials, please contact us a [email protected] In the fast-paced and highly regulated world of pharmaceutical and biotechnology research, the demand for efficient and reliable statistical programming...

Patricio Ledesma ( B.Eng Concordia University, Montreal, Canada and Master’s Degree in Clinical Trials, University of Seville, Spain) is the Head of Clinical Operations and Founder at Sofpromed CRO. Patricio is a professional consultant providing comprehensive, one-stop expert advice and guidance to biotechnology and pharmaceutical companies worldwide in the field of clinical trials and drug development. He is personally and enthusiastically devoted to helping biotech Chief Executive, Operations, Scientific, Medical, and Regulatory Officers in the planning and execution of phase I-IV clinical trials across North America, Europe, Asia-Pacific, Latin America, and Middle East regions. You can contact Patricio at: +34 607 939 266  [email protected]  

Switch language:

• Analyst Comment

ICON tops list of most-used contract research organisations in 2024

ICON’s service portfolio includes adaptive trials, biosimilars, clinical research services, resourcing solutions and laboratory services.

• Share on Linkedin
• Share on Facebook

Contract research organisations (CROs) are companies that are contracted to provide support to pharmaceutical, biotechnology and medical device companies to successfully complete product development. This includes, but is not limited to, clinical trial operation, patient recruitment and the design of protocols. More than 500 clinical trials have been initiated in 2024 using a CRO, with ICON the most used.

ICON is a contract research organisation headquartered in Ireland that provides specialised services that span the entire lifecycle of product development. ICON’s service portfolio comprises adaptive trials, biosimilars, clinical research services, commercialisation and outcomes, consulting, provision of functional services, medical imaging, resourcing solutions and laboratory services, strategic support, and tactical solutions for traditional, in vitro diagnostic and software devices.

Go deeper with GlobalData

Immuno-oncology (IO) - Thematic Intelligence

Loa and ptsr model - icon-1 in choroidal neovascularization, data insights.

The gold standard of business intelligence.

Find out more

Related Company Profiles

More than 500 clinical trials have been initiated in 2024 using a cro.

68% of ICON clinical trials are currently ongoing, with the most recent commencing on 5 August 2024. The Phase I trial, A Study to Evaluate Zilucoplan Injected Subcutaneously Either by a Prefilled Syringe or an Auto-injector in Healthy Adult Participants , will be sponsored by Belgian company UCB and is expected to end in November 2024.

The main drug candidate being tested is zilucoplan, an immunosuppressive agent formulated as a solution for the subcutaneous route of administration for the treatment of myasthenia gravis. The trial will look to enroll a total of 14 patients at the Pharmaceutical Research Associate Group BV, located in Groningen, the Netherlands.

ICON has three planned clinical trials for the last four months of 2024: Phase I trials for the treatment of ulcerative colitis and Covid-19, and a Phase II trial for the treatment of dengue fever.

How well do you really know your competitors?

Access the most comprehensive Company Profiles on the market, powered by GlobalData. Save hours of research. Gain competitive edge.

Your download email will arrive shortly

Not ready to buy yet? Download a free sample

We are confident about the unique quality of our Company Profiles. However, we want you to make the most beneficial decision for your business, so we offer a free sample that you can download by submitting the below form

More Relevant

Evommune enrols first subject in chronic inducible urticaria therapy trial

Onward wins grant from christopher & dana reeve foundation to advance bci study, dr.noah biotech's phase i trial of als treatment receives approval from fda, theolytics secures grant from innovate uk for phase i trial of ovarian cancer drug, sign up for our daily news round-up.

Give your business an edge with our leading industry insights.

Sign up to the newsletter: In Brief

Your corporate email address, i would also like to subscribe to:.

I consent to Verdict Media Limited collecting my details provided via this form in accordance with Privacy Policy

Thank you for subscribing

View all newsletters from across the GlobalData Media network.

Strategies for commercialising oncology treatments for young adults

Icon innovation.

Our experience, knowledge and technological advancements converge to shape a better future for healthcare.

Applying AI to manage the risks and costs of postmarketing requirements

Translating intent to impact.

The triad of trust: Navigating real-world healthcare data integration

Uncover how reshaping data and integration strategies can empower your organisation.

Ensuring the validity of clinical outcomes assessment data

Important considerations and best practices for effective COA implementation.

Advancements in Artificial Intelligence for site selection

Using human-enabled AI to enhance decision-making and minimise risk.

A multifaceted risk factor: Addressing obesity's impact across the disease spectrum

Considerations for clinical trial design focused on obesity treatments.

Featured Solutions

Blended solutions

Bespoke, seamless solutions to meet unique sponsor challenges.

Digital Health Technologies

ICON acquires HumanFirst, a cloud-based technology company for life sciences supporting precision measurement in patient centred clinical research.

ICON provides full service outsourcing and flexible support for biotech specific needs such as due diligence and asset valuation.

Cardiac Safety Solutions

End-to-end cardiac safety solutions, including ECG, event monitoring, BPM, long-term Holter monitoring, ECHO and MUGA studies.

Early Clinical and Bioanalytical Solutions

Innovative early clinical solutions that will advance your drug development strategy.

Site & Patient Solutions

Transforming recruitment through patient-centric trials and real-world, real-time data.

Market Access

Expertise in mission-critical pricing, market access, and reimbursement. 

Specialty Laboratory Solutions

Supporting precision medicine programs across all phases of drug diagnostic co-development.

Considerations for Oligonucleotide therapeutics in CMC

4 September 2024. Register today.

Regulatory submission writing for NDA success

10 September 2024. Register today.

Singlicate ADA analysis

11 September 2024. Register today.

ICON Insights

• 02 Sep 2024

Outcome Measures: Driving forward patient-centered clinical trials

• 28 Aug 2024

Enabling a new way to select fit-for-purpose COAs to simplify clinical protocols

• 19 Aug 2024

Enhancing diversity in clinical trials with AI and human expertise

• 14 Aug 2024

The rise of precision outcome measures

Understanding China's 2024 NRDL: Key changes and their impact

The race to develop combination vaccines – and the importance of indirect effects

Unlocking quality in machine translation: The impact of ISO 18587 certification on clinical research

• 02 Aug 2024

Outcome measures: Driving precision health strategies forward

Digital endpoints widely adopted in pharmaceutical and biotech-sponsored clinical trials

What’s happening in icon, how can we help.

• Cell and Gene Therapies
• Early Clinical
• Medical Device
• Rare & Orphan Diseases
• Real World Evidence
• Site & Patient Recruitment
• Strategic Solutions
• Regulatory Intelligence

Working together, we can reimagine medicine to improve and extend people’s lives.

Clinical Development Functional Head

About the role, are you ready to become the clinical development functional head you will lead the strategic and operational planning and management of the assigned clinical program(s) from an end-to-end clinical operations perspective. you will have complete budget oversight and resource allocation.  you will drive operational excellence through process improvement and knowledge sharing across the function. this role bridges key partners to assist the successful delivery of the novartis portfolio. you will provide support to the cd head in driving disease area strategy in one or several therapeutic areas., key requirements:.

• Serves as the main point of contact for Clinical Development associates regarding knowledge of best practices, lessons learned and issue escalation.
• Strategic partner to the Clinical Development Head with respect to various internal and external interactions and partner management as appropriate across all relevant line functions.
• Builds best talent and an empowered culture within program(s) and DU to foster high performance in a matrix environment.
• Assess needs of the organization to improve the medical/scientific, operational and budget management capabilities in assigned franchise, in collaboration with all relevant stakeholders.
• As a senior member of the Portfolio Strategy & Operations team, responsible for developing and maintaining a strong portfolio view in order to identify agile and innovative resourcing methodologies to staff programs across all clinical functions.
• Leads aal job profile optimisation, recruiting, interviewing, hiring and role onboarding activities for respective development unit clinical development associates.

Your Experience:

• Advanced degree in life sciences / healthcare is required.
• 7 years of involvement in clinical research or drug development spanning clinical activities in Phases I-IV
• 3-5 years of contribution in all aspects of conducting clinical trials – planning, implementing, reporting and publishing.
• Demonstrated ability to establish strong scientific partnership with key collaborators.
• Proficient English language skills.

Why Novartis:  Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting, and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together?  https://www.novartis.com/about/strategy/people-and-culture

Commitment to diversity & inclusion:, novartis is committed to building an outstanding, inclusive work environment and diverse team’s representative of the patients and communities we serve., join our novartis network:, not the right novartis role for you sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up:  https://talentnetwork.novartis.com/network.

Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture

Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network

Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

• Skip to Content
• Skip to Search

03 September 2024

Issued: London, UK

For media and investors only

GSK aims to redefine the future of respiratory medicine at the European Respiratory Society International Congress

• First presentation of SWIFT-1 and SWIFT-2 phase III trial data for ultra-long-acting biologic depemokimab in severe asthma
• GSK aspires to change the course of disease, reversing disease damage and, for patients with asthma, achieve long-term clinical remission
• 56 abstracts to advance scientific understanding and support GSK’s ambition to improve the lives of millions of people with respiratory conditions

GSK plc (LSE/NYSE: GSK) will share latest research findings from across its diverse respiratory portfolio of innovative therapies, including targeted biologics, vaccines and inhaled medicines, at the 2024 European Respiratory Society (ERS) International Congress in Vienna (7-11 September). The research, including three late-breaking abstracts, demonstrates the company’s commitment and ongoing ambition to redefine the future of respiratory medicine and deliver the next generation standard of care for millions of people affected by respiratory conditions like asthma, chronic obstructive pulmonary disease (COPD), refractory chronic cough and respiratory syncytial virus (RSV).

GSK’s ambitious goals build on decades of expertise, research and collaboration as the company works to reduce the global burden of respiratory diseases by providing protection from infections and the associated complications, preventing exacerbations, cumulative lung damage and disease progression while providing optimal treatment of symptoms. This means aiming for clinical remission for as many people with asthma as possible at the earliest point in their disease journey to protect their future health.

Study results from SWIFT-1 and SWIFT-2

The first presentation of the positive results from SWIFT-1 and SWIFT-2, which assessed the efficacy and safety of depemokimab versus placebo in adults and adolescents with severe asthma with type 2 inflammation characterised by blood eosinophil count, will be shared in a late-breaking alert session on Monday, 9 September at 3.45 CEST. Depemokimab is the first ultra-long-acting biologic to be evaluated in phase III trials with a binding affinity and high potency for interleukin-5 (IL-5), enabling six-month dosing intervals for patients with severe asthma. Long-acting treatments that combine an extended half-life with high potency have the potential to offer sustained suppression of the underlying drivers that contribute to disease outcomes and progression for extended periods.

Clinical remission in severe asthma

Data presented at ERS for Nucala (mepolizumab) builds on the already robust and expansive data on the role of targeting IL-5. Aiming for clinical remission is a critical treatment goal for patients with severe asthma and type 2 inflammation. Further data on clinical remission provides additional insights into evidence-based management strategies with research looking at characteristics that influence clinical remission and also the role of biologic therapy in achieving this treatment goal. Additional research for Trelegy (fluticasone furoate/umeclidinium/vilanterol or FF/UMEC/VI) will also look at clinical remission as a treatment goal in in other types and severities of asthma.

Research on COPD exacerbations

A post-hoc analysis from METREX and METREO will be presented, which shows the effect of Nucala in the trial participants with or without chronic bronchitis. A poster presentation of the study design of MATINEE, the third clinical study of Nucala in COPD, will be presented. MATINEE recruited COPD patients with broad clinical presentations of chronic bronchitis and/or emphysema, along with evidence of type 2 inflammation characterised by blood eosinophil count and builds on existing data for Nucala . Research being presented at ERS also includes the latest evidence to support the use of Trelegy in COPD and more specifically advancing research of disease stability as a realistic treatment goal.

Key abstracts presented at ERS

Encouraging new data will be presented from GSK’s portfolio that could transform outcomes for patients living with respiratory disease.

About GSK in respiratory

GSK continues to build on decades of pioneering work to deliver more ambitious treatment goals, develop the next generation standard of care, and redefine the future of respiratory medicine for hundreds of millions of people with respiratory diseases. With an industry-leading respiratory portfolio and pipeline of vaccines, targeted biologics and inhaled medicines, we are focused on improving outcomes and the lives of people living with all types of asthma and COPD along with less understood refractory chronic cough or rarer conditions like systemic sclerosis with interstitial lung disease. GSK is harnessing the latest science and technology with the aim to modify underlying disease dysfunction and prevent disease progression.

GSK is a global biopharma company with a purpose to unite science, technology, and talent to get ahead of disease together. Find out more at gsk.com.

Cautionary statement regarding forward-looking statements

GSK cautions investors that any forward-looking statements or projections made by GSK, including those made in this announcement, are subject to risks and uncertainties that may cause actual results to differ materially from those projected. Such factors include, but are not limited to, those described under Item 3.D “Risk factors” in GSK’s Annual Report on Form 20-F for 2023, and GSK’s Q2 Results for 2024.

You might also like

Media contacts

Access the contact details of our media relations teams at GSK

Media library

Search and download images and B-roll video for use in the media.

We are a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together